Chronic Non-specific Neck Pain

9

Review clinical trials related to Chronic Non-specific Neck Pain. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Comparing Between Mulligan Technique and Active Release Technique in Treatment of Chronic Mechanical Neck Pain

This study will be conducted to compare between Mulligan mobilization technique and Active release technique in management of non-specific chronic neck pain as regard to neck pain, cervical range of motion and neck function.

Participants needed: 36
Trial details
Age: 18-40Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Jul 1, 2026
Eligibility criteria

Inclusion Criteria [+4]

History of previous neck surgery. [+4]

Status: Recruiting

Effects of Telerehabilitation and Supervised Clinic Based Rehab With Pain Neuroscience Education for Pain,Kinesiophobia and Functional Disability Among Chronic Non-Specific Neck Pain Patients

Chronic non-specific neck pain is a common musculoskeletal condition affecting a large proportion of the population worldwide. It is characterized by persistent neck pain lasting more than three months without a specific underlying pathology. Many patients experience ongoing symptoms such as pain, reduced range of motion, functional limitations, and psychological factors like kinesiophobia, which can negatively affect recovery and quality of life. Conventional physiotherapy, including supervised clinic-based rehabilitation, is widely used for the management of chronic non-specific neck pain. These programs typically involve exercise therapy and patient education; however, access to regular in-clinic treatment can be limited due to factors such as travel, cost, and time constraints. Telerehabilitation has emerged as an alternative approach that allows delivery of physiotherapy services through online platforms, improving accessibility and convenience for patients. In addition, pain neuroscience education (PNE) is an evidence-based strategy that helps patients understand pain mechanisms, reduce fear-avoidance behaviors, and improve treatment outcomes when combined with exercise therapy. Although both telerehabilitation and supervised clinic-based rehabilitation are effective, there is limited evidence directly comparing these two approaches when combined with standardized pain neuroscience education. Therefore, this randomized controlled trial aims to compare the effects of telerehabilitation with pain neuroscience education and supervised clinic-based rehabilitation with pain neuroscience education on pain intensity, functional disability, and kinesiophobia in individuals with chronic non-specific neck pain.

Participants needed: 45
Trial details
Age: 18-40Biological sex: AllType: InterventionalSponsor: Lahore University of Biological and Applied SciencesUpdated: Jun 29, 2026Locations: 1
Eligibility criteria

Age between 18-40 years of both male and female gender. [+3]

Any previous neck surgery or cervical trauma . [+7]

Status: Not yet recruiting

Efficacy and Safety of Acupuncture Combined With Chinese Herbal Fumigation for Chronic Non-Specific Neck Pain

Chronic non-specific neck pain is a common musculoskeletal disorder that significantly affects quality of life and functional ability. Conventional treatments often provide limited relief and may be associated with adverse effects. Acupuncture and Chinese herbal fumigation are commonly used therapies in traditional Chinese medicine and have shown potential benefits in pain relief and functional recovery. This multicenter randomized controlled trial aims to evaluate the efficacy and safety of acupuncture combined with Chinese herbal fumigation in patients with chronic non-specific neck pain. A total of 120 participants will be randomly assigned to three groups: acupuncture combined with Chinese herbal fumigation, acupuncture combined with sham fumigation, and acupuncture alone. All participants will receive five treatment sessions within three weeks, followed by a four-week follow-up period. The primary outcome measure is pain intensity assessed using the Visual Analog Scale (VAS). Secondary outcome measures include the Neck Disability Index (NDI), cervical range of motion, Pittsburgh Sleep Quality Index (PSQI), quality of life scale, and Central Sensitization Inventory (CSI). This study aims to provide high-quality clinical evidence regarding the effectiveness of acupuncture combined with Chinese herbal fumigation for chronic non-specific neck pain.

Participants needed: 120
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Universiti Tunku Abdul RahmanUpdated: Apr 13, 2026Locations: 1
Eligibility criteria

Aged 18 to 65 years, any gender [+5]

Presence of confirmed cervical disc herniation, nerve compression, or other spec... [+7]

Status: Not yet recruiting

Effects of Transcutaneous Neuromodulation and Cervical Exercise in Students With Chronic Nonspecific Cervical Pain

This randomized controlled trial aims to compare the effectiveness of a cervical exercise program, transcutaneous neuromodulation of the spinal accessory nerve, and a placebo intervention on pain intensity, pressure pain threshold, cervical proprioception, functional disability, depression, anxiety, and stress in university students with chronic non-specific neck pain. The study will include a six-week intervention period with pre- and post-treatment assessments. The findings may contribute to the development of accessible physiotherapy interventions within university settings.

Participants needed: 51
Trial details
Age: 18-30Biological sex: AllType: InterventionalSponsor: Universidad Francisco de VitoriaUpdated: Mar 9, 2026
Eligibility criteria

University students aged 18-30 years [+3]

Specific cervical pathology (e.g., radiculopathy) [+7]

Status: Recruiting

Telerehabilitation, Face-to-Face Exercises, and a Mixed Model in Chronic Non-Specific Neck Pain

The goal of this clinical trial is to compare the effectiveness of different physical therapy delivery models in treating chronic non-specific neck pain in adults aged 20-40 years with a history of neck pain for three months or longer. The main questions it aims to answer are: * Which approach (tele-rehabilitation, face-to-face exercises, or a mixed model) is most effective at reducing neck pain intensity and functional disability? * Are there significant differences between the three models in improving cervical range of motion, kinesiophobia (fear of movement), patient satisfaction, and adherence to the exercise program? Researchers will compare three groups to see if the delivery model affects outcomes: 1. A tele-rehabilitation group receiving real-time, video-guided exercise sessions. 2. A face-to-face group receiving traditional, in-person supervised exercise sessions. 3. A mixed-model group receiving a combination of both tele-rehabilitation and face-to-face sessions. Participants will: * Be randomly assigned to one of the three groups. * Engage in a structured exercise program for 45-60 minutes per session, three times a week for six weeks. * Follow a phased exercise protocol that begins with mobility and pain reduction, progresses to strengthening, and finishes with endurance and functional training. * Complete assessments for pain, disability, range of motion, and other outcomes at the beginning and end of the 6-week intervention, with a final follow-up at 3 months.

Participants needed: 68
Trial details
Age: 20-45Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Mar 2, 2026Locations: 1
Eligibility criteria

Adults (20-40 years) with chronic non-specific neck pain (≥3 months' duration). [+1]

Neck pain due to specific pathologies (e.g., fractures, infections, or malignanc... [+2]

Status: Not yet recruiting

Mckenzie Versus Maitland Cervical Mobilization Technique in Management of Non-specific Neck Pain.

This study will be conducted to compare between Mckenzie exercises and Maitland cervical mobilization technique in management of non-specific neck pain as regard to neck pain, cervical range of motion, neck function and cervical proprioception.

Participants needed: 45
Trial details
Age: 18-29Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Dec 18, 2025
Eligibility criteria

45 Subjects diagnosed and referred from orthopedist with chronic NSNP. [+5]

History of cervical surgery. [+12]

Status: Not yet recruiting

Impact Of Cervical High-Intensity Resistive Exercises In Patients With Chronic Non-Specific Neck Pain

Purposes of the study To investigate the effect of adding Cervical High-Intensity Resistive Exercises to conventional physical therapy in patients with Chronic Non-Specific Neck Pain

Participants needed: 34
Trial details
Age: 20-40Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Aug 20, 2025Locations: 1
Eligibility criteria

Thirty-four patients diagnosed CNSNP. [+8]

History of whiplash injury. [+6]

Status: Recruiting

Predictive Variables of Outcome in Subjects With Chronic Rachialgia Referred to Different Pathways of Physiotherapy.

The aim of this study is to investigate the predictive value of various biopsychosocial variables on the outcomes of subjects with chronic spinal pain undergoing public health rehabilitation pathways. Secondly, the study aims to assess the reliability of certain questionnaires, classified as Patient-Reported Outcome Measures (PROMs), which are frequently used in the evaluation of spinal pain but whose metric properties have not yet been established. These objectives will be pursued through two comprehensive assessment sessions (before and after rehabilitation), a re-test session immediately before rehabilitation (to evaluate the reliability of the questionnaires in stable subjects), and two follow-up assessments at 3 and 6 months after discharge.

Participants needed: 200
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Fondazione Don Carlo Gnocchi OnlusUpdated: Apr 8, 2025Locations: 1
Eligibility criteria

Age of majority; [+4]

Subjects with cognitive impairment

Status: Not yet recruiting

Instrument-Assisted Soft Tissue Mobilization Versus Muscle Energy Technique on Chronic Non-specific Neck Pain

the aim of this study is to investigate if there is any difference between INSTRUMENT-ASSISTED SOFT TISSUE MOBILIZATION and Muscle Energy Technique over sternocleidomastoid on Neck pain, Range of motion and Functional disability in patients with Chronic Non-specific Neck Pain

Participants needed: 60
Trial details
Age: 18-35Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Jan 29, 2025Locations: 1
Eligibility criteria

The subjects are of both genders, aged between 18-35 years old . [+2]

Any specific neck pathology as radiculopathy, rheumatoid arthritis, and systemic... [+4]