Health Trials

Chronic Pruritus of Unknown Origin

2

Review clinical trials related to Chronic Pruritus of Unknown Origin. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Study to Evaluate Efficacy, Safety and Tolerability of Remibrutinib in Adult Participants With Severe Chronic Pruritus of Unknown Origin (CPUO)

The purpose of this phase 3 study is to establish the efficacy, safety and tolerability of remibrutinib in adult participants with severe chronic pruritus of unknown origin (CPUO).

Participants needed: 180
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Novartis PharmaceuticalsUpdated: Jul 13, 2026
Eligibility criteria

Participant must be ≥ 18 years of age, at the time of signing the informed conse... [+8]

Any active skin conditions (e.g., atopic dermatitis, psoriasis, etc.) that may i... [+5]

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Status: Recruiting

Proof of Concept Study to Assess the Pharmacokinetics/Pharmacodynamics of Nemolizumab in Adults With Chronic Pruritus of Unknown Origin (CPUO)

The primary objective of this study is to assess the PK/PD relationship of nemolizumab in adult participants aged 18 years or above with chronic pruritus of unknown origin (CPUO) during a 16-week treatment period.

Participants needed: 50
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Galderma R&DUpdated: Jun 1, 2026Locations: 26
Eligibility criteria

Participant must be 18 years of age or older. [+9]

Known dermatologic, systemic, neurologic or psychiatric condition(s), other than... [+22]

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