CLDN18.2-positive Advanced Solid Tumor

1

Review clinical trials related to CLDN18.2-positive Advanced Solid Tumor. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

SHR-A1904 Combinations in CLDN18.2-Positive Advanced Solid Tumor

This study consists of two research phases: Phase Ib (includes dose escalation stage and efficacy expansion stage): To explore the safety, tolerability and initial efficacy of SHR-A1904 in the treatment of CLDN18.2-positive advanced solid tumors, and to determine the recommended dose and recommended population for the Phase III combination study. Phase III: A randomized, Open-Label, multicenter clinical study of SHR-A1904 combined with chemotherapy and immunotherapy Versus chemotherapy combined with immunotherapy for CLDN18.2-positive advanced solid tumors.

Participants needed: 924
Trial details
Phase: Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Shanghai Hengrui Pharmaceutical Co., Ltd.Updated: Dec 31, 2025Locations: 1
Eligibility criteria

Age 18 to 75 years old (including boundary values); [+7]

Plan to receive any other antitumor therapy during this trial; Received other in... [+17]