Clear Cell Renal Carcinoma

2

Review clinical trials related to Clear Cell Renal Carcinoma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Phase II Trial of Ivonescimab in Previously Treated Patients With Advanced Clear Cell Renal Cell Carcinoma

To learn if ivonescimab can help to control previously treated, locally advanced or metastatic ccRCC.

Participants needed: 40
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: M.D. Anderson Cancer CenterUpdated: May 15, 2026Locations: 1
Eligibility criteria

Participants with histologically or cytologically confirmed metastatic/advanced... [+18]

Participants must not have any other malignancies within the past 2 years except... [+26]

Status: Not yet recruiting

Zanzalintinib for Metastatic Clear Cell Renal Cell Carcinoma With Bone Metastases

This is a single-institution, phase 2 trial of zanzalintinib plus investigator-choice bone-strengthening agent in patients with metastatic renal cell carcinoma (RCC) with bone metastases whose disease has advanced on 1-3 prior lines of therapy, including at least one immune oncology-based (IO) therapy in the adjuvant or first-line metastatic setting.

Participants needed: 20
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Kelly Fitzgerald, MDUpdated: May 1, 2026Locations: 1
Eligibility criteria

Participants must have unresectable advanced or metastatic RCC with a predominan... [+26]

Prior treatment with zanzalintinib for RCC. [+38]