Club Foot

4

Review clinical trials related to Club Foot. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Comparison of Radiological Outcome of Conventional vs Accelerated Ponseti Casting Technique for Treatment of Club Foot

Club foot (congenital talipes equinovarus) is a common birth deformity affecting 1-2 per 1,000 live births, with even higher rates in low-income countries. The standard treatment is the Ponseti method using weekly serial casts, but weekly visits for several weeks can be challenging for families in hot climates or with limited resources. This randomized controlled trial compares the standard once-weekly Ponseti casting with an accelerated twice-weekly casting technique. The primary outcome is radiological correction measured by the lateral talocalcaneal angle (target ≥35°) on standardized foot X-rays taken six weeks after brace fitting. Secondary outcomes include the talocalcaneal index (\>40) and the tibio-calcaneal (dorsiflexion) angle (60-90°). Babies under six months of age with idiopathic club foot will be randomly assigned to either the standard or accelerated casting group. All other aspects of the Ponseti method (manipulation, number of casts, tenotomy when needed, final cast for three weeks, and foot abduction orthosis) remain identical. Adverse events such as skin problems, swelling, or cast complications will be recorded. The study aims to determine whether accelerated casting achieves better radiographic correction without increasing risks.

Participants needed: 144
Trial details
Age: 1-5Biological sex: AllType: InterventionalSponsor: Khyber Medical University PeshawarUpdated: Apr 28, 2026Locations: 1
Eligibility criteria

Syndromic club foot (e.g., associated with arthrogryposis, myelomeningocele, or... [+2]

Status: Recruiting

Effects Of French Method With/Without Brace In Clubfoot Treatment

The current study will be a randomized control trial. Data will be collected from the Pakistan Society for the Rehabilitation of the Disabled, Lahore (PSRD) and the Children Hospital and Institute of Child Health, Lahore. The study will include 18 patients, equally divided into two groups and randomly allocated. Inclusion criteria will be children aged 0 to 12 months diagnosed with CTEV of either gender. Patients with neurological conditions, other orthopedic issues, previous surgical history related to the foot, severe systemic disorders, or neuromuscular disorders will be excluded from the study. The experimental group will receive the French method along with a foot abduction brace, while the control group will receive only the French method without the brace. Outcomes to be analyzed will include foot position, severity of deformity, and functional mobility. Data collection will occur before and after the intervention, utilizing clinical assessments for foot position, the Pirani score for severity of deformity, and standardized mobility assessments. Data will be analyzed using SPSS version 23.00.

Participants needed: 18
Trial details
Age: 1-12Biological sex: AllType: InterventionalSponsor: Riphah International UniversityUpdated: Feb 24, 2026Locations: 1
Eligibility criteria

Patients under 12 months of age with clubfeet. [+2]

Patients with prior clubfoot surgery were excluded. [+1]

Status: Recruiting

Comparing Outcomes and Complications Following Mastisol Application for Clubfoot Casting

The purpose of this study is to assess if the application of Mastisol, a liquid adhesive, improves outcomes during bilateral clubfoot casting and reduces complications and development of complex clubfoot for the duration of their casting and up to 5 years follow-up.

Participants needed: 100
Trial details
Age: 0-12Biological sex: AllType: InterventionalSponsor: University of Wisconsin, MadisonUpdated: Feb 19, 2026Locations: 1
Eligibility criteria

Patients with bilateral clubfeet [+3]

Patients who do not have bilateral clubfoot [+3]