Coccydynia

7

Review clinical trials related to Coccydynia. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Ultrasound-Guided Dextrose Prolotherapy for Coccydynia: A Prospective Study

Coccydynia is a musculoskeletal condition characterized by pain in the coccygeal region, particularly exacerbated by sitting, and is associated with impaired quality of life and functional limitation. Although various conservative and interventional treatment options are available, there remains a need for effective and safe alternative therapies, especially in treatment-resistant cases. Prolotherapy is a regenerative treatment modality that aims to reduce pain and improve function by stimulating tissue repair, particularly in ligamentous structures. While there is increasing evidence supporting its effectiveness in mechanical musculoskeletal pain conditions, the literature regarding its use in coccydynia is limited. The aim of this study is to evaluate the effect of dextrose prolotherapy on pain severity and functional status in patients diagnosed with coccydynia. This study is designed as a prospective, single-arm, open-label interventional study. Patients will receive 15% dextrose prolotherapy according to a standardized protocol. Pain severity will be assessed using the Visual Analog Scale (VAS), and functional status will be evaluated using the Dallas Pain Questionnaire before treatment and at 1 month after completion of the treatment. This study aims to provide more comprehensive data on the effectiveness and safety of prolotherapy in coccydynia and to contribute to the currently limited evidence in the literature.

Participants needed: 30
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: Gaziosmanpasa Research and Education HospitalUpdated: May 4, 2026Locations: 1
Eligibility criteria

Age between 18 and 75 years [+2]

Age <18 years or >75 years [+9]

Status: Recruiting

The Effectiveness of Dextrose Prolotherapy in Patients With Coccydynia

In this prospective, randomized, controlled, double-blinded study, we aimed to evaluate the effects of Dextrose Prolotherapy injections in patients with coccydynia.

Participants needed: 40
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Istanbul UniversityUpdated: Apr 27, 2026Locations: 1
Eligibility criteria

Patients with coccydynia lasting longer than 6 months, [+3]

Patients with a history of trauma within the last 3 months or postpartum coccydy... [+11]

Status: Recruiting

Osteopathic Manual Therapy vs Ganglion Impar Block for Chronic Coccydynia

Chronic coccydynia is a condition characterized by persistent pain in the coccyx region that can significantly impair sitting tolerance, daily activities, and quality of life. Various conservative and interventional treatment options have been described, including manual therapy techniques and ganglion impar block. However, the comparative effectiveness of these approaches remains unclear. The aim of this randomized controlled study is to compare the effects of osteopathic manual therapy and ganglion impar block on pain intensity and functional disability in patients with chronic coccydynia. Participants will be randomly assigned to one of the two treatment groups. Pain severity will be assessed using the Numeric Rating Scale (NRS), and functional status will be evaluated with the Oswestry Disability Index (ODI) at baseline, week 3, and month 3. The results of this study are expected to provide evidence regarding the relative effectiveness of these two commonly used treatment methods and to guide clinicians in selecting appropriate management strategies for patients with chronic coccydynia.

Participants needed: 100
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: Istanbul Medeniyet UniversityUpdated: Feb 24, 2026Locations: 1
Eligibility criteria

Age 18-75 years [+6]

Acute coccygodynia [+7]

Status: Not yet recruiting

Comparison of Ganglion Impar Radiofrequency Ablation and Phenol Neurolysis Techniques for Chronic Coccydynia Treatment

Radiofrequency ablation and phenol neurolysis of the ganglion impar are methods used in cases unresponsive to medication, particularly in patients who derive short-term or partial relief from the initial ganglion impar block. In clinical practice, clinicians frequently use these two injections in patients with treatment-resistant pain who only partially benefit from the initial blockade procedure. To date, the medical literature lacks a comprehensive study comparing the efficacy of radiofrequency ablation and phenol neurolysis in patients who partially benefit from ganglion impar block. Therefore, this study is designed to compare the effectiveness of these two methods in patients with chronic coccydynia.

Participants needed: 30
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Marmara UniversityUpdated: Jun 17, 2025Locations: 1
Eligibility criteria

Age between 18 and 65 years [+3]

History of surgery involving the sacrococcygeal region [+8]

Status: Not yet recruiting

Ultrasound Guided Ganglion Impar Block

The aim of this study is to evaluate feasibility, reliability and short term effectiveness of ganglion impar block with ultrasound in patients with chronic coccygodinia.

Participants needed: 30
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Başakşehir Çam & Sakura City HospitalUpdated: Mar 20, 2025Locations: 1
Eligibility criteria

Age between 18-65 years. [+4]

Local infection at the injection site. [+3]

Status: Recruiting

Comparison of Impar Ganglion Block and Sacral Erector Spinae Plane Block in Patients with Coccygodynia

Coccygodynia is a condition that causes pain in the tailbone (coccyx) area. While it can develop after trauma, such as a fall or fracture, in some cases, no clear cause is identified. Patients who do not experience relief from standard treatments like pain medications, physical therapy, and posture adjustments may be referred to specialized pain management clinics for further treatment options. Several interventional procedures can help manage coccygodynia. These include impar ganglion block, radiofrequency ablation, caudal epidural steroid injections, sacral erector spinae plane (ESP) block, and coccygeal nerve blocks. These procedures are commonly performed in pain treatment centers and aim to reduce discomfort by targeting specific nerves responsible for transmitting pain signals. Impar ganglion block is one of the most frequently used treatments for coccygodynia. It involves injecting a local anesthetic, with or without steroids, into a small nerve cluster in front of the sacrococcygeal joint. This procedure is performed under ultrasound and/or fluoroscopic (X-ray) guidance in a sterile operating room setting to ensure accuracy and safety. While the goal is to relieve pain, potential risks include temporary worsening of pain, bleeding, infection, or, in rare cases, rectal injury. Another interventional option is the sacral erector spinae plane (ESP) block, a technique that delivers local anesthetic under the erector spinae muscles in the sacrum. This procedure, also performed under ultrasound guidance in a sterile environment, is used to block pain signals from the coccyx and surrounding areas. Like the impar ganglion block, it can be effective for pain relief, but possible side effects include temporary pain increase, bleeding, and infection at the injection site. Both procedures are minimally invasive.

Participants needed: 130
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Başakşehir Çam & Sakura City HospitalUpdated: Mar 24, 2025Locations: 1
Eligibility criteria

Those who have had chronic coccygodynia for at least 3 months [+2]

Patients who have undergone surgery to the coccyx region [+8]

Status: Not yet recruiting

Efficacy of Interventional Methods Used in the Treatment of Coccydynia

This study aims to evaluate the effectiveness of sacral erector spinae plane block and caudal epidural injection in patients with coccydynia resistant to conservative treatments. Ultrasound guidance will be used for sacral erector spinae plane block, while fluoroscopic guidance will be applied for caudal epidural injection. The effectiveness of these treatments will be assessed through face-to-face questionnaires, the Numerical Rating Scale and the Paris Functional Coccydynia Scale at first, fourth and twelfth-week follow-ups.

Participants needed: 94
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Ankara Etlik City HospitalUpdated: Oct 23, 2024Locations: 1
Eligibility criteria

Chronic coccydynia unresponsive to conservative treatment [+2]

Coagulation disorders [+9]