Cognitive Reserve

2

Review clinical trials related to Cognitive Reserve. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Cognitive Reserve and Post-Fatigue Recovery in Older Adults

As people grow older, it is common to experience a drop in physical stamina and memory functions. This can make recovering from daily physical and mental fatigue more difficult, which directly impacts an individual's independent daily life and overall quality of life. "Cognitive reserve" is a term that describes the brain's built-in resilience. Built over a lifetime through education, work, and social activities, a higher cognitive reserve acts like a buffer, helping the brain adapt to stress and aging. While research shows that a high cognitive reserve protects against conditions like dementia, we still do not fully understand how it helps older adults bounce back from normal, everyday physical and mental exhaustion. The goal of this study is to investigate how cognitive reserve levels influence how individuals aged 65 and older perceive their recovery after experiencing physical and mental fatigue. What the Study Involves The researchers will evaluate participants aged 65 and older to measure their baseline cognitive reserve levels. The study will look closely at how these levels affect the participants': Ability to cope with daily physical and mental fatigue. Need for rest and rest patterns. Time and ability to return to normal daily activities. Overall perception of their mental and physical recovery. Expected Outcome By understanding this relationship, the study aims to fill a gap in medical literature and help healthcare providers design better, more personalized rehabilitation and lifestyle support programs to improve the quality of life for older adults.

Participants needed: 400
Trial details
Age: 65-90Biological sex: AllType: ObservationalSponsor: Uşak UniversityUpdated: Jun 25, 2026Locations: 1
Eligibility criteria

being 65 years of age or older, [+1]

Being younger than 65 years old, [+2]

Status: Not yet recruiting

Use of Sevoflurane to Test Concept of Cognitive Reserve

Previous pilot study had demonstrated a correlation between cognitive reserve and BIS variability during steady state of anesthesia. This study, we intend to evaluate the association between BIS variability and emergence and recovery time from anesthesia.

Participants needed: 70
Trial details
Age: 18-90Biological sex: AllType: ObservationalSponsor: Los Angeles General Medical CenterUpdated: Jul 8, 2024
Eligibility criteria

- Minimal completion of high-school education [+7]

- History of chronic pain [+7]