Coiling Therapy

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Condition / disease
Location
Status: Not yet recruiting

Flow-diverting Devices for the Treatment of Middle Cerebral Artery Bifurcation Aneurysms

The goal of this clinical trial is to learn if flow diverter (FD) offers advantages over conventional stent-assisted coiling in the treatment of middle cerebral artery (MCA) bifurcation aneurysms . It will also learn about the safety of flow diverter (FD) treatment. The main questions it aims to answer are: Does flow diverter (FD) treatment improves the rate of complete aneurysm occlusion and patients' neurological function? Does flow diverter (FD) treatment loweres the probability of aneurysm recurrence and the occurrence of complications? Researchers will compare FD to a conventional stent-assisted coiling to see if FD treatment works better to treat MCA bifurcation aneurysms. Participants will: Undergo stent-assisted coiling or flow diverter treatment Take pre-operative and pre-discharge head MRI scans, neurological function assessments, and cognitive function assessments Visit the clinic 1 year for checkups and tests

Participants needed: 140
Trial details
Phase: Phase 4Age: 18-75Biological sex: AllType: InterventionalSponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolUpdated: Jan 28, 2026
Eligibility criteria

Unruptured wide-necked middle cerebral artery bifurcation aneurysms definitively... [+4]

Concomitant significant organ dysfunction (e.g., severe cardiac, hepatic, or ren... [+4]