COLD

2

Review clinical trials related to COLD. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Postoperative Analgesia Between Paravertebral Block and Epidural Block in Esophageal Surgery

Prevention of postoperative pain is essential for the recovery of esophageal surgery. Epidural analgesia is a traditional and standard perioperative pain management for these patients. Beneficials of epidural analgesia have been widely established. However, there are still several potential disadvantages such as perioperative hypotension, failure of administration, rare but serious neurological complications. Ultrasound-guided regional nerve block has become a widely used technique due to its low degree of trauma and precise target of action. In combined with liposome bupivacaine (LB), a new long-acting local anesthetic, was proven to have a maximum duration of 72 hours, thus improving postoperative analgesia, reducing opioid consumption, and enhancing patient satisfaction. The aim of this study was to evaluate the efficacy of TPVB liposomal bupivacaine (LB) or plane bupivacaine (SB) for Overall Benefit of Analgesic Score (OBAS) after esophageal surgery.

Participants needed: 132
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Zhejiang Cancer HospitalUpdated: Dec 30, 2024Locations: 1
Eligibility criteria

American Society of Anesthesiologist physical status I-III; [+2]

Patients with contraindications for local nerve block such as spinal anatomic st... [+4]

Status: Recruiting

Thermotherapy in Acute Nonspecific Neck Pain

Neck pain is one of the most common musculoskeletal pain disorders secondary to low back pain. Medical and non-medical treatments such as physiotherapy are applied in its treatment. Patients with nonspecific neck pain (NBA) can be treated with various interventions such as drug therapy, manual therapy, heat and exercise. Although it is frequently used in clinical practice, there is no evidence that superficial thermotherapy (hot or cold) methods effectively relieve neck pain. Therefore, this study aims to compare the short-term effects of superficial hot or cold applications on pain, range of motion and functional status in patients with NBA.

Participants needed: 60
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Acibadem UniversityUpdated: Jul 18, 2024Locations: 2
Eligibility criteria

Being diagnosed with nonspecific neck pain by a doctor, [+7]

Not meeting the inclusion criteria, [+6]