Colon Cancer, Obstruction

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Condition / disease
Location
Status: Not yet recruiting

Outcome of Neoadjuvant Chemotherapy for Obstructive Colon Cancer

In this study, patients with obstructive colon cancer will be divided into two groups; in the control group, curative surgery will be performed within 2 weeks after successful SEMS placement, and in the experimental group, 3 cycles of neoadjuvant chemotherapy will be administered into patients who undergo successful SEMS placement and then curative surgery will be performed after neoadjuvnat chemotherapy. After the surgery, adjuvant chemotherapy will be administered, and total perioperative chemotherapy will be administered with 12 cycles. The primary end points is overall survival, also the short-term perioperative outcomes and long-term oncological outcomes will be compared between the control and experimental group. Random allocation will be carried out with the consent of patients and their guardians after successful SEMS placement, and 204 patients will be distributed between the two groups by 1:1.

Participants needed: 204
Trial details
Age: 20-74Biological sex: AllType: InterventionalSponsor: The Catholic University of KoreaUpdated: Sep 22, 2021
Eligibility criteria

i. Age : 20 years old or more and lesser than 75 years old ii. Agreement of this...

i. any suspicious distant metastasis ii. any other primary malignant lesion iii....