Health Trials

Complex Cardiovascular Surgery With Cardiopulmonary Bypass

2

Review clinical trials related to Complex Cardiovascular Surgery With Cardiopulmonary Bypass. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Efficacy and Safety of 4F-PCC (4-Factor Prothrombin Complex Concentrate) in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass (CPB)

This is a phase 3, multicenter, randomized, open-label, parallel-group, controlled study to assess the efficacy and safety of BE1116 compared with fresh frozen plasma (FFP) in adult participants undergoing complex cardiovascular surgery with CPB. The primary purpose of the study is to compare the efficacy of BE1116 and FFP in correcting coagulation factor deficiencies in bleeding participants undergoing complex cardiovascular surgery with CPB.

Participants needed: 200
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: CSL BehringUpdated: May 11, 2026Locations: 18
Eligibility criteria

Adult greater than or equal to (≥) 18 years and has provided written informed co... [+3]

Administration of any systemic hemostatic therapy, such as cryoprecipitate, plat...

Read more
Status: Not yet recruiting

Jafron Cytokine Adsorber During Pediatric Open-Heart Surgeries

This prospective single-center randomized controlled trial aims at evaluating the safety and feasibility of an hemoadsorption protocol using Jafron HA-60 during cardio-pulmonary bypass in 20 pediatric patients undergoing open-heart surgery.

Participants needed: 20
Trial details
Age: Up to 10Biological sex: AllType: InterventionalSponsor: Centre Hospitalier Universitaire VaudoisUpdated: Feb 10, 2026Locations: 1
Eligibility criteria

Children ≤ 10 years old at study inclusion [+3]

Children having an indication to receive hemoadsorption during CPB for drugs rem... [+7]

Read more