Contracture Scar

2

Review clinical trials related to Contracture Scar. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Autologous Point-of-Care Adipose Therapy: Recent Injury

The goal of this study is to explore if an adipose-based therapeutic strategy can treat full-thickness soft-tissue trauma wounds in injured individuals, especially those with severe burns or soft-tissue loss. The main question it aims to answer are: \- Can immediate autologous adipose and autologous layered composite grafting be effective for acute functional soft-tissue reconstruction? Researchers will compare the single-stage autologous layered composite grafting method to traditional methods to see if it improves healing outcomes, minimizes scarring, and reduces infection risk. Participants will: * Receive immediate fat grafting into the wound. * Undergo simultaneous split-thickness skin grafting for full soft-tissue reconstruction.

Participants needed: 68
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of PittsburghUpdated: Nov 5, 2025Locations: 2
Eligibility criteria

The proposed study will include adult patients 18 years of age or older, [+7]

Age < 18 years of age, [+6]

Status: Not yet recruiting

Autologous Point-of-Care Adipose Therapy: Delayed Injury/Scar

The goal of this study is to explore if an adipose-based therapeutic strategy can treat contracted scars secondary to soft-tissue burn wounds in injured individuals, especially those with severe burns or soft-tissue loss. The main question it aims to answer are: \- Can autologous layered composite grafting demonstrate non-inferiority compared to full-thickness skin grafting for delayed reconstruction of post-burn or trauma scar contracture? Researchers will compare the single-stage autologous layered composite grafting method to traditional methods to see if it improves healing outcomes, minimizes scarring, and reduces infection risk. Participants will: * Receive fat grafting at time of scar revision. * Undergo simultaneous split-thickness skin grafting for full soft-tissue reconstruction.

Participants needed: 40
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of PittsburghUpdated: Nov 5, 2025Locations: 2
Eligibility criteria

The proposed study will include adult patients 18 years of age or older, [+4]

Age < 18 years of age, [+6]