COPD Acute Exacerbation

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Review clinical trials related to COPD Acute Exacerbation. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Rademikibart Add-on Treatment of an Acute COPD Exacerbation (Seabreeze STAT COPD)

This is a Phase 2, multicenter study in adult participants with an acute COPD exacerbation and type 2 inflammation

Participants needed: 160
Trial details
Phase: Phase 2Age: 40-80Biological sex: AllType: InterventionalSponsor: Connect Biopharm LLCUpdated: Jun 12, 2026Locations: 53
Eligibility criteria

Physician-diagnosed COPD with duration of ≥12 months. [+6]

Regular use of immunosuppressive medication 12 weeks or 5 half-lives prior to ra... [+17]

Status: Not yet recruiting

The REVIVE Pivotal Study

The goal of this study is to test whether a new treatment called the Ryme Medical Targeted Lung Denervation (TLD) Catheter is safe and effective for people with moderate to severe chronic obstructive pulmonary disease (COPD). The main questions it aims to answer are: 1. Does the TLD Catheter improve symptoms in people with COPD? 2. Is the TLD Catheter safe ? Researchers will compare the group receiving the TLD treatment to the group receiving a sham procedure to see if the treatment improves quality of life. Participants will: 1. Be randomly assigned to receive either the TLD treatment or a sham procedure. 2. Undergo the assigned procedure in a hospital setting. 3. Attend follow-up visits for health checks and breathing tests.

Participants needed: 300
Trial details
Age: 40-80Biological sex: AllType: InterventionalSponsor: Ryme Medical, Inc.Updated: May 5, 2026
Eligibility criteria

Symptomatic chronic obstructive pulmonary disease [+3]

Prior lung intervention with device in place [+3]

Status: Not yet recruiting

Efficacy Of Inpatient Pulmonary Rehabilitation Program In Elderly Patients With Acute Exacerbation Of COPD

The study aimed to identify the effect of early pulmonary rehabilitation in elderly patients with Acute exacerbation (AE) of COPD (AECOPD) in exercise tolerance, dyspnea, sleep quality, fatigue, and time to discharge from hospital.

Participants needed: 60
Trial details
Age: 65-78Biological sex: AllType: InterventionalSponsor: Al-Azhar UniversityUpdated: Jun 13, 2025Locations: 1
Eligibility criteria

Patients with acute exacerbation of COPD in both gender [+3]

Patient with systolic blood pressure lower than 90 mmHg [+1]