Status: Recruiting
Losartan for Corneal Fibrosis
This is a prospective, randomized, double-blinded, controlled clinical trial designed to evaluate the efficacy and safety of topical losartan in improving visual acuity, contrast sensitivity and reducing corneal densitometry, corneal aberrations and corneal scarring severity in adult patients with corneal scars of different etiologies. Participants will be randomly assigned to receive either topical losartan 0.8 mg/mL or placebo eyedrops 6 times per day for six months.
Participants needed: 46
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Universidad Autonoma de Nuevo LeonUpdated: May 8, 2026Locations: 1
Eligibility criteria
Adults aged 18 years or older [+5]
Refusal or inability to provide written informed consent [+4]