Health Trials

Corneal Transplant Failure

2

Review clinical trials related to Corneal Transplant Failure. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty

The main objective of this study is to determine the safety of Ex Vivo Cross Linking (CXL) of donor corneal tissue in participants who have undergone high-risk penetrating keratoplasty.

Participants needed: 96
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Massachusetts Eye and Ear InfirmaryUpdated: Apr 21, 2026Locations: 12
Eligibility criteria

Age 18 and older [+4]

History of Stevens-Johnson syndrome or ocular pemphigoid [+12]

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Status: Recruiting

The Viability Control of Human Endothelial Cells Before Keratoplasty (V-CHECK) Study

The purpose of this international cohort study is to validate a new method for preoperative assessment of endothelial viability in donor corneal tissues for transplantation, and to correlate endothelial health as assessed by the surgical team to functional and structural long-term outcomes in the cohort of patients receiving them.

Participants needed: 135
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Azienda Socio Sanitaria Territoriale degli Spedali Civili di BresciaUpdated: Oct 2, 2025Locations: 12
Eligibility criteria

Age older than 18 years old [+3]

Prior corneal transplantation [+8]

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