Couples

3

Review clinical trials related to Couples. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Developing and Testing an Online Intervention for Alcohol and Cannabis Misuse and Healthy Relationship Skills Among Young Adult Couples

The goal of this clinical trial is to develop and test a brief online intervention to reduce alcohol and cannabis misuse and improve healthy relationship skills among young adult couples. The main questions it aims to answer are: * Will the intervention be feasible and acceptable to young adult couples? * Will the intervention demonstrate initial efficacy in reducing risky substance use and increasing relationship functioning? Eligible couples will complete a virtual baseline session and be randomized to intervention condition (online intervention with 3-5 weeks of self-paced modules) or control condition (no intervention). Couples will complete two follow-up surveys (post-assessment - approximately 5 weeks after baseline, 3-month). Couples in the control condition will be offered the intervention after 3-month follow-up. Researchers will compare intervention and control groups to see if there there is a difference between the groups on substance misuse and relationship functioning at post-assessment and 3-month follow-up.

Participants needed: 60
Trial details
Age: 18-29Biological sex: AllType: InterventionalSponsor: University of WashingtonUpdated: May 6, 2026
Eligibility criteria

Both partners in the couple are 18-29 years old [+6]

Couples who endorse any perpetration or receipt of severe interpersonal aggressi...

Status: Recruiting

Advancing Couple and Family Alcohol Treatment Through Patient-Oriented Research and Mentorship

Intimate partner violence (IPV) is a serious public health problem that results in significant health and economic burdens including mortality, morbidity, and poor treatment outcomes. A well-developed field of research suggests that alcohol misuse and posttraumatic stress disorder (PTSD) can lead to IPV. Individuals with PTSD and/or problematic drinking behaviors are at risk for IPV because of several factors that are common symptoms of PTSD. Because individuals with PTSD often drink alcohol to "self-medicate" or cope with distressing PTSD symptoms, PTSD co-occurs with alcohol misuse and alcohol use disorder at extraordinarily high rates. However, few studies have examined the combined effects of alcohol misuse and PTSD on any form of violence. This study will examine the effects of alcohol misuse and posttraumatic stress disorder (PTSD) on alcohol-related intimate partner violence (IPV). We will examine these associations among couples (N=70) in a controlled laboratory setting using validated, standardized methods in a 'real-world' settings using 28 days of ecological momentary assessment (EMA).

Participants needed: 140
Trial details
Age: 21+Biological sex: AllType: InterventionalSponsor: Medical University of South CarolinaUpdated: Apr 3, 2026Locations: 1
Eligibility criteria

Any gender identity; any race or ethnicity; ages 21 years or older. [+4]

Possible drug use disorder (except caffeine or nicotine) as meeting DSM-5 diagno... [+8]

Status: Recruiting

A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers

The purpose of this pilot study is to examine the feasibility and acceptability of a brief psychotherapy intervention to improve psychosocial coping and maintain couple relationships among young adults (aged 25-39) with cancer and their caregiving partners.

Participants needed: 20
Trial details
Age: 25-39Biological sex: AllType: InterventionalSponsor: Massachusetts General HospitalUpdated: Jan 12, 2026Locations: 4
Eligibility criteria

Either: (1) Currently receiving active cancer treatment (n=5) or are within two... [+2]