Critically-ill Patients Admitted to the ICU for Acute Respitatory Failure, Regardless the Aetilogy

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Condition / disease
Location
Status: Not yet recruiting

Use of Simplified Lung Ultrasound Score for Predicting ICU Outcomes in Patients With Acute Respiratory Failure

This study aims to Primary Aims: Verify the predictability of the PLIS at admission in predicting major clinical outcomes including: * ICU mortality (or discharge) and time to death (or discharge) * Escalation of ventilatory support antibiotic therapy or supportive medications (inotropes, steroids, sedation, neuromuscular blockers). Secondary Aims: * Determine the correlation between initial PLIS and the degree of disease severity (as evaluated per SOFA and APACHE II scores) * Determine the correlation between initial PLIS and partial pressure of oxygen in arterial blood (PaO2) to Fraction of inspired oxygen (FiO2): PaO2/FiO2 * Explore the potential association between the type of ventilatory support, ventilatory settings and PLIS at different time points. * Verify whether the site of consolidation (anterior vs. posterior lung zones) can reliably predict mortality in in ALI patients. * Determine the correlation between the PLIS score and the degree of ALI as quantified by CT of the chest (whenever a CT study is available) at the time of admission.

Participants needed: 72
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Assiut UniversityUpdated: Nov 7, 2024
Eligibility criteria

Age is or more than 18 years old. [+2]

Co- existing chronic lung disease, pathology of which is known display abnormali... [+2]