Health Trials

CRPC

2

Review clinical trials related to CRPC. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Castrate Resistant Prostate Cancer Enhertu Therapy

Use of Enhertu as a Subsequent Line of Therapy in HER2-Positive Metastatic Castration-Resistant Prostate Adenocarcinoma.

Participants needed: 60
Trial details
Phase: Phase 2Age: 18+Biological sex: MaleType: InterventionalSponsor: Washington D.C. Veterans Affairs Medical CenterUpdated: Apr 13, 2026Locations: 1
Eligibility criteria

Pathologically confirmed adenocarcinoma of the prostate [+11]

History of interstitial lung disease or pneumonitis requiring steroids [+2]

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Status: Recruiting

A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors

This is a Phase 1/2a, first-in-human, open-label study of JAB-8263, this study has two parts: solid tumor dose escalation and expansion study and hematology tumor dose escalation and expansion study. These two parts will determine the maximum tolerated dose (MTD), recommended Phase 2 dose (RP2D) and assess the DLT of JAB-8263 in treatment with patients with advanced solid tumors and hematology tumors separately. 30 subjects each will be enrolled.

Participants needed: 152
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Jacobio Pharmaceuticals Co., Ltd.Updated: Jan 9, 2026Locations: 1
Eligibility criteria

Subject must be ≥18 years-of-age at the time of signature of the informed consen... [+6]

History (≤3 years) of cancer that is histologically distinct from the cancer und... [+16]

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