Status: Not yet recruiting
Cefazolin Antibiotic Prophylaxis in Ventricular Shunt Surgery: Determination of Cerebrospinal Fluid Concentration During Valve Implantation
The objective is to determine the concentration of cefazolin in the cerebrospinal fluid after a recommended antiobiotic prophylaxis by 2g of cefazolin. Our main hypothesis is that the concentration is insufficient to protect the valve from infections. The secondary objective is to compare our results to known pharmacokinetic models of cefazolin diffusion in the literature. If differences are found we would like to search clinical features that could explain it.
Participants needed: 15
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University Hospital, Strasbourg, FranceUpdated: Aug 8, 2025Locations: 1
Eligibility criteria
Age <18 years old [+8]