Dehiscence Wound

3

Review clinical trials related to Dehiscence Wound. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Efficacy Evaluation of ActiGraft in Secondary Closure of Abdominal Surgical Wound Dehiscence

This is a prospective, single arm study, consisting of 20 women with abdominal surgical wound dehiscence that requires secondary closure. The participants will receive a weekly application of ActiGraft for 4 weeks, or until complete healing of the wound (the earlier of the two). An historic matched-control group of 20 patients will be compared retrospectively

Participants needed: 20
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: RedDress Ltd.Updated: Nov 15, 2024Locations: 1
Eligibility criteria

Age >18 years [+5]

Patients with necrotizing fasciitis [+5]

Status: Not yet recruiting

Barbed Suture vs Non-Barbed Closure for Emergency Exploratory Laparotomy RCT

This randomized control trial aims to compare the efficacy of triclosan-coated barbed suture (TCB) versus conventional non-barbed polydioxanone (PDS) suture in the closure of the abdominal fascia after emergency exploratory laparotomy. The study addresses the common complications of incisional surgical site infections (SSI) and fascial dehiscence (FD) following emergency exploratory laparotomy. The primary objective is to assess the effectiveness of triclosan-coated barbed suture and conventional non-barbed suture in reducing the rates of incisional SSI and FD within 30 days postoperatively. The study population comprises adult patients undergoing emergent laparotomy for traumatic injuries or acute intraabdominal pathology. This prospective, single-blinded randomized control trial will be conducted at Los Angeles General Medical Center. Patients will be randomized to receive either triclosan-coated barbed suture or conventional non-barbed suture for abdominal fascial closure, with a standard closure technique employed. Patients will be followed up for 30 days postoperatively to monitor surgical site infections, fascial dehiscence, and other outcomes. Statistical analysis will be conducted to compare outcomes between the study arms, assessing the efficacy of triclosan-coated barbed suture in reducing the incidence of SSI and FD, along with secondary outcomes.

Participants needed: 250
Trial details
Age: 18-100Biological sex: AllType: InterventionalSponsor: University of Southern CaliforniaUpdated: Nov 28, 2023Locations: 1
Eligibility criteria

All adult individuals aged 18 years or older who undergo emergent laparotomy via... [+1]

Individuals under 18 years of age [+11]

Status: Recruiting

Conservative Treatment or Resuturing Among Women With Perineal Wound Dehiscence After Vaginal Labour

The goal of this observational study is to make us more aware of the short and long-term outcomes for women having an uncomplicated healing process after a rupture or birth cut in the perineum after giving birth in relation to a healing process with a dehisced wound treated with conservative management or secondary suturing. Participants will be asked to do * A gynecological examination at one month after birth and 9-12 months after birth. * Have a picture taken of the healing process * Answer a questionnaire at one month, three months, and 9-12 months after birth

Participants needed: 300
Trial details
Age: 18+Biological sex: FemaleType: ObservationalSponsor: Herlev HospitalUpdated: Sep 18, 2023Locations: 1
Eligibility criteria

Women with a vaginal delivery who have had a primary repair of a second-degree p... [+3]

None, first, third- and fourth-degree tear [+1]