Demodex Blepharitis

2

Review clinical trials related to Demodex Blepharitis. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Demodex Blepharitis in Scleral Lens Wearers

The purpose of this study will be to see if Xdemvy (lotilaner ophthalmic solution) 0.25% has a positive impact on ocular surface symptoms and PROSE device functionality and performance. The investigators hypothesize the use of Xdemvy in subjects utilizing PROSE treatment will be well tolerated and that the reduction in Demodex mite load on the eyelid margin will result in reduced ocular surface symptoms and improved PROSE tolerance and functionality.

Participants needed: 5
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Boston SightUpdated: May 1, 2026
Eligibility criteria

Written Informed Consent has been obtained prior to any study-related procedures... [+6]

Is currently participating in any other type of eye-related clinical research st... [+9]

Status: Recruiting

Evaluation of the Safety and Efficacy of GLK-321 in Subjects With Demodex Blepharitis

This is a randomized, double-masked, placebo-controlled, dose-ranging, parallel-group, multi-center study designed to evaluate the safety and efficacy of GLK-321 in patients with Demodex blepharitis.

Participants needed: 250
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Glaukos CorporationUpdated: Feb 27, 2026Locations: 1
Eligibility criteria

Signs of Demodex blepharitis in at least one eye [+1]

Presence of eczema or dermatitis in the ocular region of either eye [+4]