Dental Diseases

7

Review clinical trials related to Dental Diseases. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Dental Dyschromia and Quality of Life in Early Prolonged Hyperbilirubinemia

The main objective of this study is to assess the prevalence of dental discoloration (dental dyschromia) in children who experienced high levels of bilirubin in their blood (hyperbilirubinemia) during their early years. The study will also examine risk factors associated with this condition, such as the duration and severity of hyperbilirubinemia, underlying diseases, and treatments received. The researchers hypothesize that the quality of life of individuals with dental dyschromia is lower than that of individuals without dyschromia. The results of this study will be used to discuss coverage for dental care with health insurance for children affected by this condition.

Participants needed: 120
Trial details
Age: 12-18Biological sex: AllType: ObservationalSponsor: University Hospital, ToulouseUpdated: May 12, 2026Locations: 9
Eligibility criteria

A patient with biliary atresia, progressive familial intrahepatic cholestasis, o... [+1]

Inability to understand and respond to quality of life questionnaires

Status: Recruiting

MOLAR: Mapping Oral Health and Local Area Resources

The goal of this clinical trial is to test the impact of a screening and linkage intervention for adverse social determinants of health (aSDoH) on oral health linkage to care for emergency department patients. Researchers will compare three groups: Patients in Arm A will receive paper handouts with general oral health and aSDoH resources. Patients in Arm B will receive paper handouts with geographically-proximate oral health and aSDoH resources. Patients in Arm C will receive geographically-proximate oral health and aSDoH resources plus active navigational assistance.

Participants needed: 2,927
Trial details
Age: 1+Biological sex: AllType: InterventionalSponsor: Massachusetts General HospitalUpdated: Apr 9, 2026Locations: 1
Eligibility criteria

No evidence of lack of capacity to provide verbal informed consent (as documente... [+7]

Patients on involuntary holds (per electronic medical record review) [+3]

Status: Recruiting

Antimicrobial Effect of Tropolone Containing Versus Tropolone Free Mouthwash

The objective of this study is to compare the effect of Tropolone containing mouthwash versus CHX 0.2% mouthwash in reducing intraoral microorganism. Randomized clinical trial study

Participants needed: 30
Trial details
Phase: Early Phase 1Age: 18-45Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Mar 19, 2026Locations: 1
Eligibility criteria

Patients should be between 18- 45 years of age. [+2]

Patients with a compromised medical condition. [+3]

Status: Recruiting

Virtual Reality Distraction for Dental Anxiety (RCT)

The aim of this randomized clinical trial is to verify the efficacy of VR immersion over a muted cartoon on a wall-mounted TV to decrease dental fear and anxiety of children undergoing dental procedures. The study also aims to gain insight on the satisfaction of parents and healthcare providers on the use of VR during dental appointments. Main research question: Does VR immersion compare to a cartoon on a wall-mounted TV is more efficacious to decrease dental fear and anxiety of children requiring dental procedures? Participants will be playing through a VR immersive game wearing a eye-tracking VR headset that requires no movement of the head to play, facilitating the dental procedure. The investigators will take measures of the stress levels of participants and their parents using a validated stress scale and also by taking salivary samples to verify the levels of a stress biomarker (alpha-amylase).

Participants needed: 88
Trial details
Age: 6-17Biological sex: AllType: InterventionalSponsor: St. Justine's HospitalUpdated: Aug 24, 2025Locations: 1
Eligibility criteria

Aged 6 to 17 years; [+3]

Suffer from epilepsy, [+3]

Status: Recruiting

Effectiveness and Safety of Collagen Membrane (FormaAid®) in the Treatment of Periodontal Regeneration

The goal of this clinical trial is to evaluate clinically and radiographically effectiveness and products safety of the collagen membrane (FormaAid®) in the treatment of periodontal regeneration using guided tissue regeneration (GTR) performed by the trained periodontists. The main question it aims to answer are: * The difference of periodontal status: clinical attachment level (CAL), periodontal pocket depth (PPD), gingival recession (GR), gingival Index (GI) and plaque index (PI). * The difference of intrabony defect height. * The difference of gingival tissue thickness and gingival tissue volume. * The incidences of safety indicators. Participants will be randomized into either experiment group or control group, undergo guided tissue regeneration (GTR) surgery at week 1, and re-visited on week 3, 5, 13 and 27 after the GTR surgery. Researchers will compare if the test product is non-inferior to Bio-Gide.

Participants needed: 60
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Maxigen Biotech Inc.Updated: May 9, 2025Locations: 1
Eligibility criteria

Age between 18 70 years old, male or female [+9]

Have a history of severe allergies or be allergic to collagen. [+15]

Status: Not yet recruiting

Soft Tissue Graft Over Immediately Placed Dental Implant in Maxillary Molar Socket

Compare between free tissue graft of buccal pad of fat BFP and free palatal gingival tissue graft for primary soft tissue closure over immediately placed dental implant

Participants needed: 2
Trial details
Age: 18-45Biological sex: AllType: InterventionalSponsor: Mai Ahmed HaggagUpdated: Dec 12, 2024
Eligibility criteria

class one molar extraction socket

pregnant females psychiatric problems

Status: Recruiting

Clinical Evaluation of Full Contour Zirconia Chairside CAD/CAM Crowns

This investigation will be a randomized, prospective, longitudinal clinical trial to study the clinical performance of a new monolithic, zirconia material with shade, translucency and material graduation for chairside CAD/CAM crowns. The restorations will be luted either with a self-adhesive luting material or a conventional cement. The crowns will be evaluated for a period of two years.

Participants needed: 70
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Ivoclar Vivadent AGUpdated: Mar 28, 2024Locations: 1
Eligibility criteria

at least 18 years of age [+4]

Sensitive teeth [+5]