Dental Plaque Accumulation

6

Review clinical trials related to Dental Plaque Accumulation. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

3D Volumetric Plaque Assessment on Teeth, Composite Restorations, and Ceramic Veneers Using an Intraoral Scanner

The goal of this observational study is to evaluate and compare a 3D intraoral scanner-based, computer-assisted approach for assessing dental biofilm/plaque accumulation on natural teeth and restorative surfaces with a conventional clinical plaque index (Turesky modified Quigley-Hein Plaque Index, TMQHPI) in systemically healthy adults. The main questions it aims to answer are: * How well does the plaque-covered surface measurement derived from 3D intraoral scanner data agree with TMQHPI scores after plaque disclosure? * How sensitively do the two methods detect changes in plaque levels after supervised toothbrushing? * Do plaque accumulation patterns differ between natural tooth surfaces and restorative materials (direct composite restorations and indirect ceramic veneers), and where are plaque-retentive areas most frequently located? Participants (≥18 years) will receive routine professional mechanical plaque removal as part of standard clinical care. They will then be asked to avoid mechanical and/or chemical plaque control for 4 days. At the follow-up visit, participants will undergo: 1. An intraoral scan and standardized photographs of the full dental arch, 2. Plaque disclosure followed by repeat scanning/photography and TMQHPI scoring by a periodontist, 3. Supervised toothbrushing using the modified Bass technique for 2 minutes, followed by a final scan and photographs. Digital models will be used to quantify plaque-covered surface measures and to generate 3D maps of plaque-retentive areas.

Participants needed: 45
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Trakya UniversityUpdated: Feb 23, 2026Locations: 1
Eligibility criteria

18 years or older.  [+7]

Diagnosis of gingivitis or periodontitis.  [+13]

Status: Recruiting

6-month Clinical Investigation Assessing the Efficacy of an Antimicrobial Mouthrinse in Reducing Established Plaque and Improving Gum Health

The goal of this clinical trial is to evaluate the clinical efficacy of an antimicrobial mouthrinse, with a particular focus on its effect on established plaque and the improvement of gum health. Participants will: * Brush and rinse twice a day with the designated products for 6 months * Visit the clinic once every 3 months after baseline for reassessment.

Participants needed: 90
Trial details
Phase: Phase 4Age: 18-70Biological sex: AllType: InterventionalSponsor: Colgate PalmoliveUpdated: Feb 17, 2026Locations: 1
Eligibility criteria

Male and female subjects aged 18-70 years, inclusive. [+6]

Be under orthodontic treatment. [+15]

Status: Recruiting

Comparing the Antiplaque Effects of Novel Titania Nanoparticle Infused Fluoride Varnish vs Conventional Fluoride Varnish in Fixed Orthodontic Patients.

In this study the investigators aimed to explore the antibiofilm effect of fluoride varnish loaded with titania nanoparticles synthesized from moringa oleifera leaves extract vs conventional fluoride varnish in multibracket fixed orthodontic patients.

Participants needed: 20
Trial details
Age: 16-30Biological sex: AllType: InterventionalSponsor: Pakistan Institute of Medical SciencesUpdated: Sep 25, 2025Locations: 1
Eligibility criteria

Patients planned for fixed orthodontic treatment. [+3]

Patient undergoing any antibiotic therapy. [+2]

Status: Recruiting

Evaluation of a Novel Dual-Headed Toothbrush Design for Periodontal Health: Split-Mouth Randomized Blind Clinical Trial

The goal of this clinical trial is to evaluate the effectiveness and patient satisfaction of a novel dual-headed toothbrush design compared to a conventional single-headed toothbrush in adult dental professionals aged 22-45 years with healthy gingival conditions. The main questions it aims to answer are: Does the dual-headed toothbrush improve plaque removal efficiency compared to a single-headed toothbrush? Does the dual-headed toothbrush enhance brushing comfort, reduce brushing time, and improve user satisfaction? Researchers will compare the side of the mouth (cleaned with a dual-headed toothbrush) with the other side (cleaned with a single-headed toothbrush) in a randomized split-mouth design to see if the novel design leads to superior plaque control and better user experience. Participants will: Receive both toothbrush types (medium bristle) and identical toothpaste Be trained in the Bass brushing technique Use each toothbrush, twice daily, with the assigned toothbrush applied to its designated side of the mouth Complete post-trial questionnaires on comfort, ease of use, and brushing time

Participants needed: 40
Trial details
Age: 25-40Biological sex: AllType: InterventionalSponsor: Dar Al Uloom UniversityUpdated: Sep 11, 2025Locations: 1
Eligibility criteria

• Dentists with a minimum of 26 natural teeth, good general health, and the abil... [+3]

• Participants with active periodontal disease, orthodontic appliances, or havin... [+2]

Status: Recruiting

4-day Plaque Accumulation Model Evaluating Compound Containing Gum

This will be a single-blind, single-center, 3-way crossover, randomized controlled clinical trial with 3 treatment periods utilizing 32 subjects. (Fig 1, in protocol) Each treatment period will be 4 days (96 hours +/-3 hours) in accordance with the plaque accumulation model using one of the following treatment groups: an active compound MIIP-E2 gum (experimental regimen), an inactive compound gum (negative control regimen), and a no-gum (control regimen).

Participants needed: 32
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Lactea Therapeutics, LLCUpdated: Aug 27, 2025Locations: 1
Eligibility criteria

Adult subjects between 18 and 65 years old [+5]

Presence of any acute or chronic condition, organ system disease, or medication... [+12]

Status: Not yet recruiting

Adjunctive Oral Hygiene Aids in Reducing Oral Hygiene Parameters Among Orthodontic Patients

Adult orthodontic patients aged 18-30 were included in a randomised, singleblind clinical research using a split-mouth design at a dental clinic. Both theWaterflosser® and the Super-Floss® water flossers are manufactured by Oral-B.

Participants needed: 102
Trial details
Age: 18-35Biological sex: AllType: InterventionalSponsor: sudhir rama varmaUpdated: Jan 22, 2025Locations: 1
Eligibility criteria

Participants aged 18-35 years undergoing orthodontic treatment and [+1]

Participants not undergoing orthodontic treatment and participants undergoing or... [+2]