Diabetic Pruritus

1

Review clinical trials related to Diabetic Pruritus. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Efficacy of Pregabalin for Diabetic Pruritus - A Randomized Controlled Study.

Brief Summary: The goal of this randomized controlled study is to learn if pregabalin combined with emollients can reduce pruritus (itching) in people with Type 2 Diabetes Mellitus. The main questions it aims to answer are: Does pregabalin combined with emollients reduce pruritus severity compared to a placebo combined with emollients? What is the impact of pregabalin on the quality of life of participants suffering from diabetic pruritus? we will compare pregabalin plus emollient to a placebo plus emollient to see if pregabalin works better for reducing pruritus. Participants will: Receive either pregabalin 75 mg daily along with emollient therapy or a placebo along with emollient therapy. Visit the clinic at weeks 4, 8, and 12 for follow-up assessments, including: Pruritus severity using the Visual Analog Scale (VAS) and 5-D Itch Scale. Patient Global Impression of Change (PGIC) to measure overall improvement. This study will help determine if pregabalin, a drug used for neuropathic pain, can be an effective treatment for pruritus in people with diabetes.

Participants needed: 46
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Post Graduate Institute of Medical Education and Research, ChandigarhUpdated: Jan 5, 2026Locations: 2
Eligibility criteria

Adults (>18 years) with Type 2 Diabetes Mellitus [+4]

Pruritus of less than six weeks' duration. [+5]