Disc Herniation, Lumbar

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Review clinical trials related to Disc Herniation, Lumbar. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Biologic Injection For Adults With Lumbar Disc Herniation

The goal of this clinical trial is to find out whether adding a bone-marrow aspirate concentrate (BMAC) injection during surgery can improve recovery in adults undergoing lumbar microdiscectomy for a lumbar disc herniation. The main questions it aims to answer are: * Does the BMAC injection lead to better disc tissue health after surgery (as seen on MRI scans)? * Does the BMAC injection lead to greater improvement in pain and disability compared to surgery alone? Participants will be adults aged 18 and older who are scheduled for lumbar microdiscectomy surgery. Researchers will compare one group of participants receiving the standard-of-care surgery plus the BMAC injection with another group receiving the same surgery without the injection to see if the injection offers added benefit. Participants will: * Have surgery (microdiscectomy) with or without the injection. * Complete pain and disability questionnaires at several times over 2 years. * Undergo MRI scans at baseline and follow-up to assess disc structure and tissue health. * Provide samples of leftover disc or bone-marrow tissue (as applicable) from surgery for analysis.

Participants needed: 90
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Weill Medical College of Cornell UniversityUpdated: Apr 16, 2026Locations: 1
Eligibility criteria

Male or female patients ≥ 18 years of age [+3]

Prisoners [+10]

Status: Recruiting

Smartwatch Accuracy for Measuring Vitals and Anxiety Before Disc Surgery

This study aims to verify the accuracy of blood pressure, heart rate, blood oxygen saturation, anxiety level, and sleep cycle data measurements obtained from Samsung smartwatches compared to the currently accepted method used in patients with disc herniation undergoing the preoperative period.

Participants needed: 60
Trial details
Age: 22+Biological sex: AllType: ObservationalSponsor: Halil KalaycıUpdated: Jan 7, 2026Locations: 1Duration: 3 Months
Eligibility criteria

22 years and older [+5]

Patients who are currently receiving prescribed medication specifically for slee... [+2]