Distal Hypospadias

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Review clinical trials related to Distal Hypospadias. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Fibrin-Enhanced TIP Versus Grafted TIP Urethroplasty in Distal Hypospadias

Hypospadias is a common congenital condition in boys in which the opening of the urethra is located on the underside of the penis. Distal hypospadias is the most common form and is usually treated surgically using tubularized incised plate (TIP) urethroplasty. In boys with an unfavorable urethral plate, graft-augmented techniques (G-TIP) are often used; however, postoperative complications such as urethrocutaneous fistula and narrowing of the urethral opening (meatal stenosis) may still occur. Platelet-rich fibrin (PRF) is a biological material obtained from the patient's own blood that contains natural growth factors and may help improve tissue healing. This study aims to evaluate whether the use of PRF during surgery can reduce postoperative complications and improve surgical outcomes in children undergoing hypospadias repair.

Participants needed: 100
Trial details
Age: 6-84Biological sex: MaleType: InterventionalSponsor: National Children's Medical Center, UzbekistanUpdated: Jan 30, 2026Locations: 2
Eligibility criteria

Male children aged 6 months to 84 months [+4]

Disorders of sex development or ambiguous genitalia [+5]