Health Trials

Dominant Dystrophic Epidermolysis Bullosa

2

Review clinical trials related to Dominant Dystrophic Epidermolysis Bullosa. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa

KB803-EYE-01 is a Phase 3 double-blind, randomized, placebo-controlled, crossover study to evaluate the safety and efficacy of KB803 versus matched placebo in pediatric and adult subjects with recurrent corneal abrasions due to dystrophic epidermolysis bullosa (DEB).

Participants needed: 16
Trial details
Phase: Phase 3Age: 6+Biological sex: AllType: InterventionalSponsor: Krystal Biotech, Inc.Updated: Mar 12, 2026Locations: 5
Eligibility criteria

The subject and/or their parent/legal guardian must provide informed consent/ass... [+3]

Initiation of any new treatment regimen or change in treatment for ocular diseas... [+5]

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Status: Recruiting

Long-Term Follow-up Protocol

The main objective of this prospective, observational, long-term follow-up (LTFU) study is to evaluate the long-term safety profile of the gene therapy products evaluated by Krystal Biotech, Inc. which have a shared backbone of HSV-1, in participants who received at least one dose of investigational product (IP).

Participants needed: 50
Trial details
Age: 6+Biological sex: AllType: ObservationalSponsor: Krystal Biotech, Inc.Updated: Jun 8, 2021Locations: 3
Eligibility criteria

All adult and pediatric participants who received at least one gene therapy trea... [+2]

Participants who enroll into a non-Krystal Biotech, Inc. interventional gene the...

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