Health Trials

Driver Mutation

2

Review clinical trials related to Driver Mutation. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Local Consolidative Radiation Therapy Plus TKI Versus TKI Alone in Driver Mutated OM-NSCLC

A Phase II randomized controlled trial of TKI Alone versus TKI and Local Consolidative Radiation Therapy in oncogene driver mutated oligo metastatic Non-small cell lung cancer patients.

Participants needed: 106
Trial details
Phase: Phase 2Age: 18-99Biological sex: AllType: InterventionalSponsor: Tata Memorial HospitalUpdated: Sep 10, 2025Locations: 1
Eligibility criteria

Patients with pathologically proven diagnosis of NSCLC [+10]

Patients with progressive disease after 2-3 months of initial TKI therapy [+9]

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Status: Recruiting

Lung Cancer Screening of Family Members of Patients With Mutation-Driven Lung Cancer

This is a single-armed screening research study which screens immediate family member of lung cancer patients with a driver mutation to see if lung cancer can be inherited and whether researchers can find lung cancer early. Immediate family members of lung cancer patients will be 40-80 years old and screened using a low dose CT scan.

Participants needed: 1,753
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: University of California, IrvineUpdated: Jul 14, 2025Locations: 1
Eligibility criteria

Current diagnosis of lung cancer with a driver mutation. [+3]

There are no exclusion criteria for Cohort A. [+14]

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