Drug Effects

2

Review clinical trials related to Drug Effects. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Modulation of Gut MicroFLORA With Rifaximin to Reduce High Platelet Reactivity in Post-ACS Patients on Ticagrelor

The FLORA-ACS study aims to evaluate the relationship between dysbiosis and high platelet reactivity during treatment with ticagrelor in patients with a history of acute coronary syndromes and investigate the use of rifaximin to eliminate dysbiosis and thus provide effective antiplatelet treatment.

Participants needed: 50
Trial details
Phase: Phase 4Age: 18-80Biological sex: AllType: InterventionalSponsor: Collegium Medicum w BydgoszczyUpdated: Oct 2, 2025Locations: 1
Eligibility criteria

Between 18 and 80 years of age [+4]

History of hypersensitivity to rifaximin or other rifamycin-derived agent [+11]

Status: Recruiting

The Efficacy of a Smart Phone-based Test on Measuring Pupillary Light Reflex Alterations Following Cannabis Use Healthy in Adults

The goal of this open label study is to evaluate the efficacy of smart phone-based test (SOBEREYE OPTOVERA) on measuring pupillary light reflex (PLR) alterations following cannabis use healthy in adults. The main question it aims to answer is: Can SOBEREYE OPTOVERA detect PLR alterations following cannabis consumption in healthy adults, in comparison to a pupillometer? Participants will be given two 5 mg capsules to be ingested for the 10 mg THC dose or five 5 mg capsules to be ingested for the 25 mg THC. Participants will be asked to complete PLR tests throughout the study day.

Participants needed: 20
Trial details
Age: 21+Biological sex: AllType: InterventionalSponsor: Sobereye Inc.Updated: Jul 17, 2025Locations: 1
Eligibility criteria

Males and females 21 years of age or older [+12]

Individuals who are pregnant, breast feeding or planning to become pregnant duri... [+22]