Status: Recruiting
Opioid Drug Interaction Study
This study will examine the effects of doses of opioid/placebo and doses of alprazolam/placebo, alone and in combination. The primary outcomes are pharmacodynamic measures (subjective ratings of drug liking and other abuse-related effects; physiological outcomes) and pharmacokinetic outcomes (from blood samples) to determine the interaction effects of these compounds.
Participants needed: 25
Trial details
Phase: Phase 1, Phase 2Age: 18-55Biological sex: AllType: InterventionalSponsor: Shanna Babalonis, PhDUpdated: May 14, 2026Locations: 1
Eligibility criteria
English-speaking and literate participants, able to understand and sign Informed... [+8]
physical dependence on alcohol, opioids, benzodiazepines or sedative/hypnotics r... [+9]