DSD

2

Review clinical trials related to DSD. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Breaking Silence Through Story: A Narrative Medicine Intervention for Parents of Children With Urogenital Conditions

The goal of this clinical trial is to learn whether a journaling intervention can reduce stress and anxiety in parents of children with urogenital conditions (such as differences of sex development and hypospadias). The main questions it aims to answer are: * Does guided journaling help to reduce anxiety levels in parents of children with urogenital conditions? * What are parents' perspectives on group-based writing interventions for future support programs? Participants will: * Complete a short anxiety questionnaire (the General Anxiety Disorder-7 scale) at the beginning of the study * Receive a physical journal with 5 writing prompts designed to help process emotions related to their child's condition * Complete 5 journal entries over several weeks, writing about their experiences and feelings * Complete the same anxiety questionnaire again after finishing the journal entries * Participate in a 45-minute interview to discuss how the journaling affected their stress levels and gather feedback on potential group-based writing programs

Participants needed: 20
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Sarah SchlegelUpdated: May 18, 2026Locations: 1
Eligibility criteria

Parent or legal guardian of a child (age 0-17 years) diagnosed with a urogenital... [+4]

Parent/guardian with severe psychiatric disorder that would interfere with parti... [+2]

Status: Recruiting

Minipuberty in Infants Born With Potential Hypogonadism Hypogonadotrope

Disorders of sex development (DSD) occur in 1/3000 births and are defined by variation in aspect of external genital organs, e.g. cryptorchidism, hypospadias and micropenis in male infants and clitoral hypertrophy in female infants. Genetic, hormonal and environmental factors are implicated in DSD. Infants with congenital hypogonadism hypogonadotrope (CHH) can present with DSD. Evaluation of hormonal profile during minipuberty could be of great help to better characterize the etiology of DSD and CHH in particular. Our main objective is to study hormonal profile during the minipuberty of infants born with DSD or born from parents with CHH compared to controls.

Participants needed: 100
Trial details
Age: Up to 9Biological sex: AllType: ObservationalSponsor: Centre Hospitalier Universitaire VaudoisUpdated: Jul 22, 2022Locations: 1Duration: 18 Years
Eligibility criteria

infants born with symptoms of DSD [+1]

premature < 35 weeks of gestation [+1]