Health Trials

Duodenal Adenocarcinoma

2

Review clinical trials related to Duodenal Adenocarcinoma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Trial Comparing Standard of Care Therapy With and Without Sequential Cytoreductive Intervention for Patients With Metastatic Foregut Adenocarcinoma and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid (ctDNA) Levels

This is a randomized, open label, single-center, phase 2, randomized controlled trial of sequential cytoreductive intervention versus standard of care therapy for patients with intervenable oligometastatic (stage IV) cancer of the upper gastrointestinal (GI) tract and undetectable ctDNA at the time of randomization after a three-month induction chemotherapy period.

Participants needed: 54
Trial details
Phase: Phase 2Age: 18-80Biological sex: AllType: InterventionalSponsor: Yale UniversityUpdated: Jun 22, 2026Locations: 1
Eligibility criteria

Has a primary diagnosis of AJCC 8th Edition Stage IV esophageal or gastroesophag... [+22]

Has a positive urine pregnancy test within 3 days prior to randomization or trea... [+21]

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Status: Recruiting

Outcomes After Laparoscopic Versus Open Pancreaticoduodenectomy

This is a monocentric, prospective, randomized controlled trial comparing the safety and efficacy of laparoscopic pancreaticoduodenectomy (LPD) versus open pancreaticoduodenectomy (OPD). The study aims to determine the morbimortality of the laparoscopic approach compared to the gold standard open approach in adult patients with pancreatic or periampullary lesions.

Participants needed: 90
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: Minia UniversityUpdated: Jan 21, 2026Locations: 1
Eligibility criteria

Age ≥18 years. [+5]

Emergency surgery. [+9]

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