Early Parkinson Disease (Early PD)

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Review clinical trials related to Early Parkinson Disease (Early PD). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

The goal of this Phase 2 clinical trial is to investigate the efficacy and safety of NEU-411 in men and women aged 40-80 years with early Parkinson's Disease (PD) who have predicted elevations in the activity of the "leucine-rich repeat kinase 2" ("LRRK2" for short) pathway based on their genetic profile. A DNA test will be used to identify the "LRRK2-driven" population with predicted elevation in the LRRK2 pathway.

Participants needed: 150
Trial details
Phase: Phase 2Age: 40-80Biological sex: AllType: InterventionalSponsor: Neuron23 Inc.Updated: Jul 1, 2026Locations: 70
Eligibility criteria

Aged 40-80 years at time of screening, inclusive [+3]

Secondary or atypical parkinsonian syndromes [+2]