Status: Recruiting
A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
The goal of this Phase 2 clinical trial is to investigate the efficacy and safety of NEU-411 in men and women aged 40-80 years with early Parkinson's Disease (PD) who have predicted elevations in the activity of the "leucine-rich repeat kinase 2" ("LRRK2" for short) pathway based on their genetic profile. A DNA test will be used to identify the "LRRK2-driven" population with predicted elevation in the LRRK2 pathway.
Participants needed: 150
Trial details
Phase: Phase 2Age: 40-80Biological sex: AllType: InterventionalSponsor: Neuron23 Inc.Updated: Jul 1, 2026Locations: 70
Eligibility criteria
Aged 40-80 years at time of screening, inclusive [+3]
Secondary or atypical parkinsonian syndromes [+2]