Edentulous Jaw

8

Review clinical trials related to Edentulous Jaw. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Accuracy of Complete-Arch Implant Photogrammetry

This prospective comparative clinical study evaluated the accuracy and chairside time of complete-arch implant scans obtained using an intraoral photogrammetry system and a mobile-phone-based photogrammetry system in edentulous patients rehabilitated with complete-arch implant-supported prostheses. Implant positions recorded by each system were compared with a reference dataset to assess linear and angular discrepancies. The chairside time required for data acquisition was also measured. The study aimed to determine whether mobile-phone-based photogrammetry can provide clinically acceptable accuracy comparable to that of intraoral photogrammetry while improving clinical efficiency. The findings may help clinicians select appropriate digital impression techniques for complete-arch implant rehabilitation.

Participants needed: 42
Trial details
Age: 18-50Biological sex: AllType: ObservationalSponsor: Menoufia UniversityUpdated: Jun 11, 2026Locations: 1
Eligibility criteria

Adults aged 18 years or older. [+4]

Patients with unstable or failed implants. [+6]

Status: Not yet recruiting

Clinical Outcomes of 3D Printed and Milled Complete Dentures

This is a two-armed, single-center clinical study evaluating performance, efficacy and safety of three dimensional (3D) printed complete dentures and milled complete dentures during a 5-year follow-up period. The primary objective of this clinical investigation is to evaluate survival rate, i.e. subjects with survived dentures in both upper and lower jaw, of 3D printed complete dentures and milled complete dentures after 1 year (in each of the groups separately).

Participants needed: 68
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Dentsply Sirona Implants and ConsumablesUpdated: Jun 8, 2026Locations: 1
Eligibility criteria

Adult aged 18 years or above at time of informed consent. [+6]

Known allergy or hypersensitivity to any of the components. [+13]

Status: Recruiting

Primary Stability and Peri-implant Outcomes of Short Implants in Post-extraction Single-tooth Sites

The placement of short implants in post-extraction sockets is a valuable option when residual bone height is limited, minimizing morbidity and treatment time. The management of the peri-implant gap and soft tissues may influence primary stability, hard/soft tissue remodeling, and implant success.

Participants needed: 10
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: University of Bari Aldo MoroUpdated: Jan 27, 2026Locations: 1
Eligibility criteria

Age ≥18 years. [+4]

Heavy smoking (>20 cigarettes/day). [+5]

Status: Recruiting

Accuracy of Standard and Geometric Pattern-Assisted Digital Scanning for Full-Arch Implant Prosthesis Frameworks

This clinical trial aims to compare three different impression techniques used to fabricate full-arch implant-supported dental prostheses. Accurate impressions are essential to ensure a passive and precise fit of the final prosthetic framework, which contributes to long-term implant success and patient comfort. In this crossover study, participants with four osseointegrated dental implants in the lower jaw will undergo three types of impressions: Conventional splinted impression using polyvinyl siloxane (PVS) material. Standard digital impression using an intraoral scanner. Geometric pattern-assisted digital impression, which incorporates a visual reference pattern to improve scan alignment and accuracy. Each participant will receive all three impression techniques in a randomized sequence, at different time points. The accuracy of each method will be assessed by evaluating the passivity of the resulting prosthetic frameworks using two methods: (1) digital superimposition analysis to measure three-dimensional (3D) spatial deviation, and (2) the clinical "one-screw test" to detect misfit. The study seeks to determine whether digital scanning, particularly with geometric pattern assistance, can provide accuracy comparable to or better than conventional methods. Findings may guide improvements in digital prosthodontic workflows and support more efficient, predictable treatment outcomes.

Participants needed: 4
Trial details
Age: 30-70Biological sex: AllType: InterventionalSponsor: Mirna ashraf anis heneenUpdated: Jul 15, 2025Locations: 1
Eligibility criteria

Not listed

Status: Recruiting

Marginal Bone Changes in Fixed All-on-Four Mandibular Prosthesis Using OT Bridge Attachment System

Group I (control) Edentulous mandible receiving all on four fixed mandibular prosthesis using conventionally screw retained multiunit abutments. Group II (intervention) Edentulous mandible receiving all on four fixed prostheses using OT bridge attachments system. For both groups, the implant sites will be prepared aided by the surgical template. 4 implants with length 11-13 mm will be placed, two anterior implants will be aligned in an axial orientation and two posterior implants will be distally aligned according to the all-on-four concept in the inter foraminal area. Implants will be ideally placed at bone level. For both groups: After implant placement and surgical guide removal, healing abutments ( will be connected during healing periods (eight to twelve weeks). Group I ( control) After eight to twelve weeks from implant placement, multiunit abutments with appropriate heights and angulations will be connected to the implants. Group II ( intervention) After eight to twelve weeks from implant placement, narrow- and low-profile OT Equator abutment will be screwed onto the implants according to the manufacturer. marginal bone changes and prosthetic complications are the outcomes Radiographic follow up will be performed for marginal bone changes Serial of standardized digital periapical radiographs using will be taken at the time fixed prosthesis insertion (baseline), 3,6,9,12 months. Type and incidence of prosthetic complications for the prothesis for each group will be evaluated in 3, 6,9 and 12 months, these complications included: loosening or fracture of the prosthetic screw, prosthesis mobility and fracture of the prosthesis.

Participants needed: 20
Trial details
Age: 40+Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Apr 25, 2025Locations: 2
Eligibility criteria

Aged 40 years or older. [+3]

General contraindications for oral surgery [+7]

Status: Recruiting

Facial Prediction Technology for Edentulous Patients

According to data from the World Health Organization, approximately 160 million people worldwide are edentulous. The incidence increases with age, and the proportion of edentulous patients is higher in the population aged 60 and above. Loss of teeth or edentulism can affect facial appearance, causing people to feel self-conscious and loss confidence in social situations, and even lead to psychological illnesses. Therefore, edentulous patients not only pay close attention to the recovery of oral function but also attach great importance to facial contour improvement. For a long time, due to technological limitations, clinicians have been unable to depict the changes in facial contour after implant placement for patients before surgery. However, with the development of artificial intelligence technology, deep learning-based methods for predicting soft tissue facial deformation have made this mission a possibility. This study established a multi-modal dataset for edentulous patients before and after implant restoration to lay the foundation for predicting facial contour changes after implant treatment. A graph generative adversarial network based on multi-modal data was proposed to achieve fast and high-precision facial contour prediction. To address the common challenges of slow computation and excessive computational resource consumption in current triangular mesh deformation simulation methods, this project innovatively proposed a graph generative adversarial network that uses multi-modal data and incorporates self-attention mechanisms to achieve fast and high-precision facial contour prediction for edentulous patients after implant restoration.

Participants needed: 24
Trial details
Age: 50-100Biological sex: AllType: ObservationalSponsor: KU LeuvenUpdated: Jun 13, 2024Locations: 1
Eligibility criteria

Patients with complete edentulism, [+2]

patients who refuse to participate in the study, [+1]

Status: Not yet recruiting

Maxillary Implant Overdentures Retained by Bars or Locator

* Background Patients experiencing problems with their conventional maxillary denture can benefit from implant- retained overdentures. Several retention systems are available. These retention systems can be roughly divided into bar-retained implant overdentures, in which multiple implants are splinted and the overdenture is attached through retentive clips, and into retention systems using non-splinted solitary attachments (locators). Evidence on maxillary implant overdenture attachment systems has been mostly short to medium term, non-comparing or retrospective. Even more, 10-years data of comparative studies are lacking. * Main research question To compare treatment outcomes of fully edentulous patients with maxillary overdentures, supported by four implants, retained by either bars or locators . The primary objective of the study is to analyze marginal bone level changes by radiological assessments at 10-years follow-up. Secondary objectives are implant and overdenture survival, condition of peri- implant mucosa and patients' satisfaction. * Design (including population, confounders/outcomes) The study design is an observational study of a group of patients which were treated 10 years ago with dental implants and an overdenture in the maxilla because of problems with retention and stability with their conventional denture. Outcomes: primary outcome is the change in marginal peri-implant bone level 10 years after placing the overdenture. Secondary outcome measures will be implant and overdenture survival, peri-implant mucosa health and patients' satisfaction using a questionnaire.

Participants needed: 50
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University Medical Center GroningenUpdated: May 9, 2024Locations: 1
Eligibility criteria

Fully edentulous patients or patients with an overdenture in the mandible, who w... [+5]

Patients with American Society of Anesthesiologists score (ASA score) ≥ III; [+3]

Status: Not yet recruiting

RCT Comparing KS Versus TS for Ovedenture

To evaluate the clinical and radiographic outcomes of KS implants used to rehabilitate edentulous mandible with dental-retained overdentures, and to compare it with same treatment on TS implants

Participants needed: 48
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Università degli Studi di SassariUpdated: Feb 26, 2024
Eligibility criteria

Any edentulous patient (post-extractive sites must to be healed from at least 3... [+3]

General contraindications to implant surgery. [+15]