Empathy

12

Review clinical trials related to Empathy. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

AI-Based Communication Simulation and Human Library Narratives.

This research plan aims to establish an effectiveness assessment system for promoting clinical communication, empathy, and emotion regulation in pediatric nursing students through a combination of AI communication simulation and human library narrative. This study sets five specific objectives: 1. To develop and implement a pediatric nursing teaching model that integrates AI communication simulation and human library narrative. 2. To evaluate the effectiveness of this teaching model in improving nursing students' clinical communication skills. 3. To examine the effectiveness of this teaching intervention in enhancing nursing students' empathy. 4. To explore the impact of this teaching intervention on nursing students' emotion regulation abilities. 5. To understand students' learning experiences, feelings, changes in emotion regulation, and suggestions for improvement regarding this integrated teaching intervention.

Participants needed: 40
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: National Defense Medical University, TaiwanUpdated: Jun 9, 2026Locations: 1
Eligibility criteria

Must be 18 years of age or older [+2]

Individuals with mental illness or cognitive impairment that may affect their pa...

Status: Not yet recruiting

A Virtual Reality Couples' Intervention for Sexual Victimization Prevention: a Gender-swapping Transformative Approach

The goal of this clinical trial is to evaluate the effectiveness of REVISE (REalidad Virtual Inmersiva y SExualidad), an immersive virtual reality (IVR) intervention designed to promote empathy and reduce sexual harassment behaviors in heterosexual cisgender men. The main questions that this study aims to answer are as follows. Does experiencing gender swapping in IVR increase empathy towards survivors of sexual harassment? Does the intervention modify attitudes toward gender roles and sexual harassment? Researchers will compare the three experimental groups to evaluate the effects of IVR: 1. Identity Exchange Group with Exposure to Sexual Harassment: Participants embodied their partner's identity in a VR harassment scenario. 2. Identity Exchange Group without Harassment Exposure: Participants embodied their partner's identity in a neutral VR scenario. 3. Third-person Observer Group: Participants observe a harassment scenario in VR from their own perspective. Participants will: 1. Attend one virtual reality session in a laboratory setting. 2. Undergo pre- and post-intervention assessments and a three-month follow-up. 3. Complete self-report questionnaires and physiological measures (eye tracking and pupillometry). 4. Participate in semi-structured interviews about their experiences. This study aims to explore how immersive VR embodiment can be used as a tool for gender violence prevention by fostering perspective-taking and behavioral change.

Participants needed: 180
Trial details
Age: 18-39Biological sex: AllType: InterventionalSponsor: Universitat Oberta de CatalunyaUpdated: Mar 23, 2026
Eligibility criteria

Participants must be between 18 and 39 years old. [+3]

Individuals with any physical condition that may hinder the use of VR equipment... [+3]

Status: Not yet recruiting

AI-Supported Empathy Mapping to Enhance Communication and Grit in Pediatric Nursing Students

The nurse-patient communication environment in pediatric care is characterized by high uncertainty and complexity. Due to children's limited language development and emotional regulation abilities, coupled with parents' high level of involvement, nursing students often experience anxiety, lack of confidence, and avoidance behaviors, which negatively affect their clinical learning outcomes and the establishment of therapeutic relationships. Therefore, providing effective communication support strategies is essential in pediatric nursing education. This study aims to implement an instructional scaffolding model using artificial intelligence (AI)-generated empathy maps to enhance the communication skills, empathy performance, and grit of nursing students during pediatric clinical practicums when encountering communication challenges. A mixed-methods research design was adopted, and the participants were third-year nursing students enrolled in a pediatric nursing practicum course. The teaching intervention included AI-assisted generation of age-appropriate communication strategies, the construction of a grit-oriented empathy map, small group scenario-based exercises, and the application of learned strategies in clinical settings. Quantitative data were collected using pre- and post-intervention assessments, including an empathy scale, a communication skills scale, and a grit scale, to evaluate changes in learning outcomes. Qualitative data, including reflective journals, clinical observations, and focus group interviews, were analyzed to explore students' learning processes and strategy adaptations. Triangulation was applied to strengthen the validity of the findings. It is anticipated that this teaching model will enhance students' understanding of pediatric patients' emotional needs, strengthen their communication strategy application and clinical interaction quality, and promote persistence and adaptability in challenging situations. Through evidence-based teaching practice, this study is expected to provide a feasible and scalable innovative instructional model that supports the effective integration of AI into clinical nursing education, thereby improving pediatric nursing competence and the quality of care for children.

Participants needed: 66
Trial details
Age: 18-25Biological sex: AllType: InterventionalSponsor: Mackay Memorial HospitalUpdated: Jan 28, 2026
Eligibility criteria

Undergraduate nursing students aged 18 years or older [+1]

Status: Recruiting

Observational Study on the Impact of Obstructive Sleep Apnea on Executive Function and Empathy Development in Children

This study aims to investigate the effects of obstructive sleep apnea (OSA) on executive function and empathy development in children aged 3-12 years. The study will compare the outcomes of different treatment approaches (surgical vs. pharmacological) in children with mild OSA and track the progression of cognitive and emotional functions over 12 months. The study will also explore potential EEG biomarkers for assessing neurological damage in OSA children.

Participants needed: 150
Trial details
Age: 3-12Biological sex: AllType: ObservationalSponsor: Children's Hospital of Soochow UniversityUpdated: Jan 26, 2026Locations: 1
Eligibility criteria

Children aged 3-12 years. [+3]

Other primary sleep disorders (e.g., narcolepsy, restless leg syndrome). [+2]

Status: Recruiting

Strengthening Relationships and Mental Health Through a Couples-Based Economic Empowerment Intervention

This sub-study is part of a larger randomized controlled trial (RCT) titled Disentangling and Preventing Economic Violence against Women (ECOVI). It is conducted in rural and urban communities across Maharashtra, Andhra Pradesh, and Rajasthan, India. The sub-study evaluates the impact of a couples-based financial literacy and gender-transformative intervention on relationship strength, empathy, and mental health among married couples. Using a two-arm cluster RCT design, 150 clusters (villages or community units) are randomized to intervention or control, with \~15 husband-wife pairs per cluster (approximately 2,250 couples in total). Outcomes are measured at baseline (pre-intervention) and endline (post-intervention) approximately six months after delivery of the intervention to assess changes in perceived relationship strength, empathy (using an adapted relationship strengths and empathy scale), and mental health (General Health Questionnaire-6, GHQ-6). The study will also explore whether improvements in relationship strength and empathy mediate the intervention's effect on mental health outcomes.

Participants needed: 4,500
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Technical University of MunichUpdated: Sep 24, 2025Locations: 2
Eligibility criteria

Women: 18 - 49 years, Men: 18+ [+5]

Either partner < 18 years [+2]

Status: Not yet recruiting

The Test of Those Managing Pain With Their Own Pain

The study aims primarily to investigate physicians' awareness of their health status, empathy towards patients, and management processes through a questionnaire targeting physicians who diagnose and manage patients' pain.

Participants needed: 175
Trial details
Biological sex: AllType: ObservationalSponsor: Haseki Training and Research HospitalUpdated: Apr 23, 2025
Eligibility criteria

Specialist physicians actively working in pain treatment and management (e.g., A... [+2]

Physicians who are not actively involved in pain management or who specialize in... [+2]

Status: Not yet recruiting

Assessment of Empathy Levels in Dental Hygiene Students and Interns

Empathy is a crucial element in the practice of dentistry, significantly influencing patient satisfaction and treatment outcomes. Recent studies have highlighted the importance of empathy in healthcare, suggesting that it is essential for effective clinician-patient communication and overall quality of care. Despite its recognized value, there is a concerning trend of declining empathy levels among dental students as they progress through their education. This decline may adversely affect their ability to connect with patients, ultimately impacting the quality of dental care provided. In Saudi Arabia, research on empathy within dental education remains limited. A study conducted at King Abdulaziz University indicated that while dental students exhibited a sense of moral obligation, their overall empathy scores were lower than anticipated1. Furthermore, factors such as gender and academic year were found to influence empathy levels, with female students generally scoring higher than their male counterparts. Another study from Dammam reported similar findings, emphasizing the need for targeted interventions to enhance empathy among dental students and interns. This proposed cross-sectional study aims to assess empathy levels among dental hygiene students and interns in Saudi Arabia. By utilizing the Jefferson Scale of Empathy-Health Profession Students (JSE-HPS), this research will explore how demographic factors such as age, gender, and academic year correlate with empathy scores. The insights gained from this study could inform curriculum development and training programs aimed at fostering empathetic communication skills among future dental professionals.

Participants needed: 200
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Qassim UniversityUpdated: Mar 20, 2025
Eligibility criteria

Dental hygiene students enrolled in accredited programs in Saudi Arabia. [+2]

Dental hygiene post-graduation student. [+4]

Status: Recruiting

Substance Use Treatment and Its Role in Supporting Social Cognition

This study aims to assess changes in empathy levels before and after residential treatment among individuals with substance use disorders.

Participants needed: 108
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Nova Southeastern UniversityUpdated: Nov 27, 2024Locations: 2
Eligibility criteria

Meet criteria for a substance Use Disorder, receiving treatment at Recovery Unpl...

Neurological disorder, severe cognitive impairment, comorbid thought disorder su...

Status: Recruiting

The Effects of Multi-Psycho-Oncology Care Courses

When the patient's mood has not yet reached a moderate to high severity level, psychological support is usually provided by the clinical nurses. However, the result of past research showed that the needs of patients and their caregivers were not satisfied with the psychological level. Scholars pointed out that it may be related to factors such as excessive clinical workload or insufficient psychological support and care capacity. In addition, under the influence of COVID-19 in the past two years, medical staff are facing more physical and mental pressure. Oncology nurses have a heavy workload and are affected by the COVID 19 epidemic, which reflects that nurses need psychological support. Therefore, this study intends to reduce stress through remote physical and mental support activities, and use the Internet to intervene in guided relaxation and meditation. Considering the scheduling of clinical nurses, a remote and unstructured course content that does not require continuity will be selected, and then advanced to provide the empathetic care skills of oncology nurses.

Participants needed: 280
Trial details
Age: 20+Biological sex: AllType: InterventionalSponsor: National Taiwan University HospitalUpdated: Nov 6, 2024Locations: 1
Eligibility criteria

Over 20 years old (inclusive) [+1]

Those who are unwilling or unable to participate in this course training for a f... [+7]

Status: Recruiting

From the Heart: Comparing the Effects of Spiritual and Secular Meditation on Psychophysiology, Cognition, Mental Health, and Social Functioning in Healthy Adults

The purpose of this study is to investigate and compare the effects of Christian and Islamic heart-centred spiritual meditation to mindfulness meditation and waitlist control conditions, respectively, in healthy adults. The potential effects will be studied at multiple levels, with a focus on psychophysiology, cognition, mental health, and social functioning.

Participants needed: 288
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: Coventry UniversityUpdated: Aug 22, 2024Locations: 2
Eligibility criteria

18 to 60 years old [+3]

currently suffer from any mental health conditions or use medication to manage m... [+3]

Status: Recruiting

Exploring Empathy and Compassion Using Digital Narratives

Stories of suffering and struggle are shared continuously through digital formats such as internet videos, news stories, social marketing, and fundraising campaigns. Digital stories are often created and shared to generate awareness about a problem, impart knowledge on contemporary issues, or promote compassion. The practice of sharing critical life events and insights provided by these experiences are valuable for tellers and the listeners alike for catharsis, healing, reconciliation, and connectiveness. Portrayals of mental suffering are a matter of cultural and social interest as new media products become available to the public. Studies published since the 1990s overwhelmingly conclude that formal media depictions are biased, promoting the stereotype that people who suffer emotionally are mentally ill, dangerous, violent, or insane. Various agencies, organizations, and corporations are actively working to provide alternative stories/narratives to mainstream media by means of video testimonials in social marketing and fundraising campaigns and, ultimately, by taking advantage of the Internet. The impact of this work is under-researched. However, preliminary evaluations of social marketing campaigns report mixed results and raise questions about their effectiveness. As well, the first-person narrative prepared digitally and shared online is also providing alternative narratives to mainstream media stories. People are increasingly using digital videos to share their stories, viewing this as an opportunity to understand their emotions and thoughts, come to terms with disgrace around sensitive, personal issues and marginalization while providing hope and encouragement to others. This proposed study focuses on the process of creating digital narratives/stories, especially stories of mental and emotional suffering, and their impact in terms of inciting empathy, compassion, and good citizenship among viewers.

Participants needed: 80
Trial details
Age: 18-35Biological sex: AllType: InterventionalSponsor: McGill UniversityUpdated: Jul 29, 2024Locations: 1
Eligibility criteria

18-35 years of age [+1]

Not in age range (18-35 years of age) [+2]

Status: Not yet recruiting

Role of Empathy in Curative Treatment Outcomes of Non-metastatic Colorectal Cancer.

The aim of project EMPACOL will be to investigate, while taking into consideration the clinical factors known and well described in the literature, among the non-clinical factors, in particular, patient-healthcare personnel (HCP) relationship, a link between HCP's empathy perceived by the patient, and the results of the curative treatment of non-metastatic colorectal cancer, throughout the patient's care.

Participants needed: 250
Trial details
Age: 18-80Biological sex: AllType: ObservationalSponsor: University Hospital, CaenUpdated: Jul 7, 2022
Eligibility criteria

Not listed