Enamel Mineralization Disorders

1

Review clinical trials related to Enamel Mineralization Disorders. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Graphene-Reinforced CAD/CAM Restorations for MIH-Affected Molars in Adolescents: A Prospective Clinical Study

This study evaluates the clinical performance, marginal integrity, surface wear, color stability, and postoperative sensitivity of graphene-reinforced CAD/CAM indirect restorations (inlays, onlays, overlays) in molars affected by moderate to severe Molar-Incisor Hypomineralization (MIH) in adolescents. A total of 30 patients aged 10-16 years will receive minimally invasive indirect restorations fabricated from a nano-reinforced graphene polymer (G-CAM®). Clinical outcomes will be assessed using FDI criteria, VAS sensitivity scores, patient satisfaction, and digital 3D scans over a 12-month follow-up. The study aims to determine clinical acceptability and safety compared with historical outcomes reported for composite and lithium-disilicate indirect restorations.

Participants needed: 30
Trial details
Age: 10-16Biological sex: AllType: InterventionalSponsor: Universitat Internacional de CatalunyaUpdated: Jan 9, 2026Locations: 1
Eligibility criteria

Adolescents aged 10-16 years. [+4]

Fluorosis, amelogenesis imperfecta, or other enamel defects. [+6]