Health Trials

Endometrioid Carcinoma

2

Review clinical trials related to Endometrioid Carcinoma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

PD-1 Inhibitor Combined With Progesterone Treatment in FST for Patients With MMRd Endometrial Cancer

The objective of this study was to investigate the feasibility of a PD-1 inhibitor in combination with progesterone as a means of preserving fertility in patients with early-stage mismatch repair-deficient (MMRd) endometrial cancer who wish to preserve fertility.

Participants needed: 10
Trial details
Age: 18-45Biological sex: FemaleType: InterventionalSponsor: Peking University People's HospitalUpdated: Aug 12, 2024Locations: 1
Eligibility criteria

Be between the ages of 18-45 years old; [+5]

Stage IB(FIGO 2009) and above； [+4]

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Status: Recruiting

Adaptive ChemoTherapy for Ovarian Cancer in Patients With Replased Platinum-sensitive High Grade Serous or High Grade Endometrioid Ovarian Cancer

ACTOv will compare standard 3-weekly carboplatin (AUC5), to carboplatin delivered according to an AT regimen. The AT regimen will modify carboplatin dose according to changes in the clinical-standard serum biomarker CA125 as a proxy measure of total tumour burden and an individual patient's response to the most recent chemotherapy treatment. AT could prolong sensitivity to carboplatin and extend tumour control, while simultaneously reducing chemotherapy dose and drug-induced toxicity. Carboplatin is a low cost and low toxicity drug that has an enduring and central role in ovarian cancer treatment.

Participants needed: 80
Trial details
Phase: Phase 2Age: 18+Biological sex: FemaleType: InterventionalSponsor: University College, LondonUpdated: Apr 12, 2024Locations: 1
Eligibility criteria

Female patients aged ≥18 years [+15]

Non-epithelial ovarian cancer, carcinosarcoma, low-grade serous and endometrioid... [+12]

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