Status: Recruiting
Whole Genome Sequencing Versus Whole Exome Sequencing for Congenital Diarrhea and Enteropahty
This study will seek to determine if whole genome sequencing (WGS) improves diagnostic rates, and outcomes for congenital diarrhea and enteropathy (CODE) patients. The investigator will enroll 180 patients in a randomized controlled study to either WGS or whole exome sequencing (WES). This study is designed to evaluate whether CODE patients would benefit from WGS guided precision medicine.
Participants needed: 180
Trial details
Age: Up to 6Biological sex: AllType: InterventionalSponsor: Children's Hospital of Fudan UniversityUpdated: Mar 24, 2026Locations: 1
Eligibility criteria
Patients with chronic diarrhea lasting greater than 2 months [+2]
Chronic diarrhea caused by specific infections, i.e. CMV, Clostridioides diffici... [+4]