Status: Not yet recruiting
A Trial of Upadacitinib for Non-responsive Eosinophilic Esophagitis
The goal of this study is to find out if a medication called upadacitinib can help treat a condition called Eosinophilic Esophagitis (EoE). The main question it aims to answer are: \- Does upadacitinib in addition to topical corticosteroids help reduce EoE disease activity? Participants will: * Take upadacitinib or placebo every day for 12 weeks, followed by 12 weeks of upadacitinib * Fill out surveys and answer health questions * Visit the clinic every 4 weeks for checkups and tests
Participants needed: 52
Trial details
Phase: Phase 2Age: 18-65Biological sex: AllType: InterventionalSponsor: University of North Carolina, Chapel HillUpdated: May 15, 2026Locations: 2
Eligibility criteria
Age 18-65 years. [+7]
Use of systemic corticosteroids (such as prednisone or methylprednisolone) withi... [+20]