Evidence-Based Practice

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Review clinical trials related to Evidence-Based Practice. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Multi-Level Strategy for De-implementing Mammography Overuse Among Older Women

This project aims to advance methodological and theoretical approaches for developing, selecting, refining, and piloting a multilevel de-implementation strategy to reduce the overuse of screening mammography in women aged ≥75 years. Informed by an innovative participatory, stakeholder-driven innovation tournament and a discrete choice experiment, the research team identified, prioritized, and tailored a multilevel de-implementation strategy. The research team will conduct a cluster randomized controlled trial (at the provider level) to test the impact of the provider- and patient-level components of the multilevel strategy on screening mammography use, and secondarily, on provider referrals/orders for screening mammography. The organizational level components of the multilevel strategy will be implemented among all participants, not via random assignment.

Participants needed: 500
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Columbia UniversityUpdated: Apr 6, 2026Locations: 1
Eligibility criteria

English- or Spanish-speaking women based on preferred language in electronic hea... [+3]

Women with a history of atypical ductal hyperplasia (ADH) or non-invasive or inv... [+6]

Status: Not yet recruiting

THE EFFECT OF DIGITAL STORYTELLING ON NURSING STUDENTS' NURSING PROCESS EDUCATION

Study Type: Randomized Controlled Experimental Study Purpose: This study aims to evaluate the effects of digital storytelling-enhanced nursing process education on nursing students' knowledge, nursing process competency, and clinical reasoning skills. The nursing process, which includes assessment, diagnosis, planning, implementation, and evaluation, forms the foundation of evidence-based and holistic care. However, the literature indicates that nursing students often face difficulties in assessment, prioritization, and individualization of care interventions and frequently apply the process mechanically. The study addresses the following primary questions: Does digital storytelling improve nursing students' knowledge of the nursing process? Does digital storytelling enhance students' nursing process competency and clinical reasoning skills? Study Design and Comparison: Participants will be assigned to either the intervention or control group based on their Nursing Process knowledge scores. Groups will be stratified by gender and knowledge test scores using a stratified randomization method to ensure balanced distribution and group homogeneity. Researchers will compare outcomes between groups to evaluate the effectiveness of the educational approach. Participants' Key Activities: Participants must be first-time enrollees in the Fundamentals of Nursing I course, have completed all course content, and have voluntarily agreed to attend. Complete pre- and post-intervention assessments, including the Nursing Process Knowledge Test, Nursing Process Competency Scale, Clinical Reasoning Assessment Rubric, and Instructional Material Motivation Scales. Engage in follow-up evaluations immediately after the intervention and three months later to assess the retention and sustainability of learning outcomes. Additional Notes: Digital storytelling materials will be validated through expert review and pilot testing. The Clinical Reasoning Assessment Rubric will undergo Turkish-language validity and reliability evaluation. Findings are expected to provide evidence on the effectiveness of digital storytelling in nursing process education, support curriculum development at the undergraduate level, and guide the broader implementation of technology-enhanced, reflective learning approaches in nursing education.

Participants needed: 104
Trial details
Age: 18-45Biological sex: AllType: InterventionalSponsor: Sakarya UniversityUpdated: Mar 25, 2026Locations: 1
Eligibility criteria

Undergraduate nursing students enrolled in the Nursing Fundamentals I course for... [+2]

Graduates of a health vocational high school [+2]

Status: Recruiting

Effect of Implementing Evidence-based Practice and Nurse's Behavior Change on Quality of Care in Intensive Care Unit: Focus on Ventilator Associated Pneumonia in a Tertiary Hospital in Bangladesh

Quality of care is crucial for preventing adverse events such as infection in the intensive care units (ICUs). The most common ICU-acquired infections include pneumonia such as ventilator-associated pneumonia (VAP), Central Line Bloodstream Infection (CLABSI), catheter-associated urinary tract in, Medical Device Related Pressure Ulcer (MDRPU) and Pressure Ulcer (PU). This study explores the patient outcome in ICU by examining the causes and prevalence of ICU-acquired infection. The implementation of evidence-based practice (EBP) to reduce infection and change the nurses practice (behavioral changes) to adhere with EBP based on simulation-based training. General objective: To evaluate the effect of EBP by using recent technologies-based equipment to prevent VAP and promote behavior change among nurses for better outcome of the patient in ICU. Specific Objectives: 1. To determine the incidence of adverse events (VAP rate, MDRPU rate, PU rate, CLABSI rate), length of stay and survival rate in ICU. 2. To evaluate the effectiveness of EBP education by changing nurses' behavior and determine its impact on improving patient outcomes in the ICU. 3. To evaluate the effectiveness of EBP including proper equipment use and changed nurses behavior acquired through the training for better patient outcome (VAP ratio) in the ICU. 4. To examine the feasibility of evaluation process and outcomes and successful implementation of EBP in ICU. Hypothesis: It is hypothesize that implementing EBP in ICU, including new equipment use and nurses training, will improve patient outcome. These research consist of three studies: Phase 1: Incidence of adverse events (VAP rate, MDRPU rate, PU rate, CLABSI rate), length of stay and survival rate in ICU. The patients of General ICU will be followed up after admission up to discharge or death at ICU. The investigators use the study findings for our subsequent intervention study 3 as historical data. Phase 2: A pre- and post- quasi-experimental study will be conducted for 6 months to evaluate the nurse's competency on EBP after getting 1-month EBP training. This study has 3 steps: (1) Pre-observation period to measure nurse's competency level for 2-month, (2) nurse's EBP training period with preparation for 1 month, and (3) post-implementation period to measure nurse's competency and implementation of EBP practice for 2 months. Study nurses will receive EBP training, EBP and proper equipment for patient management. The nurses will receive EBP education and training with necessary equipment, such as a close suction catheter, an endotracheal tube, a suction device, and a mouth care brush. In this study, use global standard equipment for the patients safety. Phase 3: A pre- and post- quasi-experimental study will be implemented to evaluate the efficacy of EBP implementation. The investigators use new equipment and implement EBP for patients and assess the patient outcomes. The investigators compare the findings from study 1 (as historical data) with the data from this study 3. The investigators will compare the VAP infection prevalence and patients' outcomes related to ICU-acquired infection between pre- and post- test phase.

Participants needed: 272
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Hiroshima UniversityUpdated: Dec 15, 2025Locations: 2
Eligibility criteria

Who will be a registered nurse in Bangladesh. [+1]

Who will not directly involve patient care in ICU. [+6]

Status: Recruiting

Online Training Course to Improve Evidence-based Leadership

The goal of this cluster clinical trial is to evaluate the effectiveness of online training course, targeted to unit leaders to improve staff's evidence-based skills (individual outcomes), EBP implementation (team-based outcomes), and the quality of care (organisational outcomes). Feasibility and fidelity of the intervention will be assessed as well. The main questions it aims to answer are: 1. Does online training course improve staff's evidence-based practice? 2. Does online training course improve staff's self-esteem and self-efficacy? 3. Does online training course improve leadership for EBP implementation on organisational level? 4. Does online training course improve the quality of patient care? 5. Does online training course reduce staff's absence (sick leaves, intention to leave the ward or hospital)? Participants will: * Participants will join in a seven-months online training course in small group or practice as usual. * Seven course modules, read course material, prepare assignments, join in peer discussions. * Self-assessment, self-reflection and give course feedback.

Participants needed: 300
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of TurkuUpdated: Jun 13, 2025Locations: 1
Eligibility criteria

have shown their willingness to join the study, [+5]

Those staff members who are off duty during the recruitment period (family leave...

Status: Not yet recruiting

Education Program on Evidence-based Practices on Nurses' Competencies and Clinical Decision-Making Levels

This clinical trial aims to develop an online education program and an educational booklet for nurses on EBP and to compare the evidence-based competencies and clinical decision-making levels of nurses trained with these two methods. Hypotheses of the Study Ho: There is no statistically significant difference between the nurses' competency levels who participated in the online education developed for evidence-based practices and those who were informed of the educational booklet. H1. The nurses' competency levels who participated in the online education developed for evidence-based practices are statistically higher than those who were informed of the educational booklet. Ho: There is no statistically significant difference between the clinical decision-making levels of nurses who participated in the online education developed for evidence-based practices and nurses who were informed with the educational booklet. H1: The clinical decision-making levels of the nurses who participated in the online education developed for evidence-based practices are statistically higher than those informed with the educational booklet. Participants will: The nurses in the intervention group are expected to fill in the data collection tools (Introductory Information Form for Nurses, Evidence-Based Practice Competency Scale, Clinical Decision Making Scale in Nursing) before the education and then participate in the education about evidence-based practices on the online platform and fill in the data collection tools (Evidence-Based Practice Competency Scale, Clinical Decision Making Scale in Nursing and Education Evaluation Form) 20 days after the education. The nurses in the control group were expected to complete the data collection tools (Introductory Information Form for Nurses, Evidence-Based Practice Competency Scale, Clinical Decision Making Scale in Nursing) before the education booklet was given and 20 days after the education.

Participants needed: 70
Trial details
Biological sex: AllType: InterventionalSponsor: Koç UniversityUpdated: Mar 10, 2025Locations: 1
Eligibility criteria

Nurses who agree to participate in the study and work in inpatient wards will be...

Nurses who do not agree to participate in the study and do not work in inpatient...