Exanguination

3

Review clinical trials related to Exanguination. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Stability of Blood Clotting Products Stored in Emergency Ambulances Under Real-World Conditions

Emergency medical service (EMS) vehicles are exposed to a wide range of environmental conditions, including high temperatures during summer months. These conditions may affect the stability and quality of medications and blood products carried for emergency treatment. This observational study aims to evaluate the stability of human fibrinogen concentrates and human plasma proteins (Octaplas) when stored under routine operating conditions in a ground-based EMS ambulance in Graz, Austria. Drug samples will be analyzed monthly over a four-month period and compared with reference samples stored under recommended conditions. In addition, temperature inside the storage containers and the vehicle will be continuously monitored. The study will assess whether prolonged exposure to real-world prehospital storage conditions affects product stability and whether any changes are associated with environmental factors. The findings may help determine whether current storage practices in EMS vehicles are adequate for maintaining the quality of these blood coagulation products.

Participants needed: 2
Trial details
Biological sex: AllType: ObservationalSponsor: Medical University of GrazUpdated: Jun 17, 2026
Eligibility criteria

Fibryga samples stored in the participating ground-based EMS ambulance. [+3]

Samples with damaged packaging. [+4]

Status: Not yet recruiting

Abdominal Aortic Junction Tourniquet (AAJT-S) for Non-compressible Torso Haemorrhage in the Prehospital and Emergency Room Setting

This study seeks to evaluate the feasibility of a Abdominal Aortic Balloon Occlusion of the Aorta (AAJT-S) in exanguinating trauma patients with non-compressible truncal haemorrhage in the emergency room and the pre-hospital setting.

Participants needed: 50
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Medical University of GrazUpdated: Dec 10, 2025Locations: 1
Eligibility criteria

Written consent of the participant after being informed [+4]

Status: Recruiting

Abdominal Aortic Junction Tourniquet (AAJT-S) for Non-compressible Torso Haemorrhage

This study seeks to evaluate the feasibility of a Abdominal Aortic Balloon Occlusion of the Aorta (AAJT-S) in exanguinating trauma patients with non-compressible truncal haemorrhage in the emergency room and the pre-hospital setting.

Participants needed: 10
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Medical University of GrazUpdated: Apr 17, 2025Locations: 1
Eligibility criteria

aged, or believed to be aged, 18 years or above, [+2]

suspected additional bleeding source proximal to the umbilicus, or [+2]