Extensive Small Cell Lung Cancer

2

Review clinical trials related to Extensive Small Cell Lung Cancer. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Phase II Study of QL1706 With Anti-angiogenesis Therapy and Chemotherapy in Extensive-stage Small Cell Lung Cancer.

This single-arm, open-label, Phase II study assesses first-line QL1706 + bevacizumab (anti-VEGF) + platinum/etoposide chemotherapy to treat naïve ES-SCLC patients.The main questions it aims to answer are: Evaluate efficacy and safety of this quadruplet regimen in ES-SCLC Explore correlations between tumor biomarkers and treatment efficacy Participants will: Histologically or cytologically confirmed, treatment-naïve extensive-stage small cell lung cancer (ES-SCLC). Willing to provide archived or fresh tumor tissue samples. If unavailable, enrollment may proceed per investigator assessment. At least one measurable lesion per RECIST v1.1

Participants needed: 56
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Zhijie WangUpdated: Jul 24, 2025Locations: 1
Eligibility criteria

Signed written informed consent and willingness to comply with study procedures. [+14]

Prior chemotherapy, immunotherapy, targeted therapy, or radiotherapy. [+20]

Status: Recruiting

Adebelizumab Combined With Chemotherapy and Radiotherapy Treat ES-SCLC

To observe the efficacy and safety of adebelizumab combined with chemotherapy and sequential adebelizumab combined with radiotherapy in the treatment of newly diagnosed extensive small cell lung cancer.

Participants needed: 51
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Qianfoshan HospitalUpdated: Nov 9, 2023Locations: 1
Eligibility criteria

Age 18-75 years old, both male and female; [+14]

Symptomatic brain metastasis and liver metastasis; [+19]