Extramedullary Multiple Myeloma

2

Review clinical trials related to Extramedullary Multiple Myeloma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Aponermin-Based Bridging Therapy Prior to CAR-T Infusion in Relapsed/Refractory Multiple Myeloma Patients With Extramedullary Disease

This is a prospective, single-arm, multicenter, open-label study to evaluate the efficacy and safety of aponermin-based bridging therapy prior to CAR-T infusion in relapsed/refractory multiple myeloma patients with extramedullary disease.

Participants needed: 20
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Institute of Hematology & Blood Diseases Hospital, ChinaUpdated: Aug 14, 2025Locations: 2
Eligibility criteria

Be informed and voluntarily sign the Informed Consent Form (ICF). [+14]

Plasma cell leukemia or solitary plasmacytoma. [+9]

Status: Recruiting

Study to Evaluate the Safety and Efficacy of Daratumumab and Carfilzomib-based Induction/Consolidation/Maintenance Therapy in Transplant-eligible, Ultra High-risk, Newly Diagnosed Multiple Myeloma

This study will assess whether the combination of daratumumab and carfilzomib-based Induction/Consolidation/Maintenance Therapy with ASCT improves the outcome of patients with ultra high-risk, newly diagnosed multiple myeloma

Participants needed: 54
Trial details
Phase: Phase 2Age: 18-70Biological sex: AllType: InterventionalSponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyUpdated: Apr 16, 2025Locations: 1
Eligibility criteria

Patients must have newly diagnosed ultra high-risk disease, as defined by one of... [+4]

No evidence of high-risk disease. [+17]