Extremely Deep Caries

4

Review clinical trials related to Extremely Deep Caries. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Influence of Proximal Caries on Outcome of Direct Pulp Capping in Permanent Mandibular Molars With Reversible Pulpitis

The aim of the study is to assess the Influence of proximal caries on outcome of direct pulp capping in permanent mandibular molars with sign of reversible pulpitis. objective- Primary objective- To evaluate and compare the clinical and radiographic outcome of Direct pulp capping in mandibular molars with occlusal and proximal carious lesions. Secondary objective- To evaluate and compare 1.OHRQoL after Direct pulp capping in occlusal and proximal lesion. 2. Postoperative pain, after Direct pulp capping in occlusal and proximal lesion Subjects of age group 15 - 40 yrs will be included and divided into two groups 1) Permanent mature molars with proximal carious lesion 2)Permanent mature molars with occlusal carious lesion.

Participants needed: 154
Trial details
Age: 15-40Biological sex: AllType: InterventionalSponsor: Postgraduate Institute of Dental Sciences RohtakUpdated: Jun 10, 2026Locations: 1
Eligibility criteria

Mature permanent mandibular molars with extremely deep caries that penetrate the... [+2]

Mechanical or pulp exposure due to trauma [+5]

Status: Not yet recruiting

Outcome of Direct Pulp Capping and Partial Pulpotomy in Reversible Pulpitis

AIM: -The aim of the study is to compare the outcome of Direct Pulp Capping and Partial Pulpotomy in mature permanent teeth with Reversible Pulpitis OBJECTIVES: - Primary Objective: to compare the difference in clinical and radiographic outcome of direct pulp capping and partial pulpotomy in mature permanent teeth with Reversible Pulpitis. Secondary objective: To evaluate and compare postoperative pain after Direct Pulp Capping and Partial Pulpotomy in teeth with Reversible Pulpitis STUDY GROUPS: - Subjects of age group 15 to 40 years will be included and divided into two groups 1. Direct Pulp Capping in Permanent mature molars with Reversible Pulpitis 2. Partial Pulpotomy in Permanent mature molars with Reversible Pulpitis

Participants needed: 138
Trial details
Age: 15-40Biological sex: AllType: InterventionalSponsor: Postgraduate Institute of Dental Sciences RohtakUpdated: Dec 23, 2025Locations: 1
Eligibility criteria

Patients aged 15-40 years. [+5]

Non restorable teeth [+11]

Status: Recruiting

Effectiveness of Pulpotomy vs. Root Canal Treatment in Extremely Deep Caries

Recent clinical trials comparing pulpotomy versus root canal treatment (RCT) have shown promising outcomes; however, the current evidence lacks generalisability to general practitioners. It remains to be elucidated whether these favourable results can be replicated in a primary care setting. This study aims to address that gap by involving senior dental students undergoing supervised university education and training, with the potential to inform future best practice guidelines and promote the adoption of vital pulp therapy (VPT) as a predictable treatment alternative in the general dental population. The clinical procedure involves complete caries-free excavation carried out under rubber dam isolation. After confirming vital pulp status-demonstrated by bleeding upon entry, participants will be randomised to receive one of two treatments: RCT or full pulpotomy. Outcomes will include clinical and radiographic success or failure of the intervention at 12 months. Additionally, patient-reported outcomes will be collected, specifically pain experienced and the use of analgesia during the immediate post-operative period (days 3 and 7).

Participants needed: 93
Trial details
Age: 12+Biological sex: AllType: InterventionalSponsor: National University Hospital, SingaporeUpdated: Nov 21, 2025Locations: 1
Eligibility criteria

Aged 12 years or older [+4]

Teeth with difficult access and unpredictable isolation using a rubber dam [+10]

Status: Recruiting

Outcome of Partial Pulpotomy in Moderate and Severe Pulpitis

The aim of the study is to compare the outcome of Partial Pulpotomy in mature permanent teeth with moderate and severe pulpitis. OBJECTIVE: Primary objective- to compare the difference in clinical and radiographic outcome of partial pulpotomy in mature permanent teeth with moderate and severe Pulpitis. Secondary objective- To evaluate and compare OHRQoL and postoperative pain after Partial Pulpotomy in teeth with Moderate Pulpitis and Severe Pulpitis. Subjects of age group 15 to 40 years will be included and divided into two groups 1. Permanent mature molars with Moderate Pulpitis 2. Permanent mature molars with Severe Pulpitis

Participants needed: 120
Trial details
Age: 15-40Biological sex: AllType: InterventionalSponsor: Postgraduate Institute of Dental Sciences RohtakUpdated: Aug 28, 2025Locations: 1
Eligibility criteria

Patients aged 15-40 years. [+6]

Non restorable teeth [+10]