Facet Joints; Degeneration

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Review clinical trials related to Facet Joints; Degeneration. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Reliability and Reproducibility of Facet Joint Measurements in the Thoracolumbar Spine

The purpose is to determine how reliably degenerative changes in the facet joints (FJs) and intervertebral discs (IvDs) can be assessed on computed tomography (CT) scans. At least six raters, including neurosurgeons and CT specialists, will independently evaluate anonymized CT scans covering the T9-L3 levels. The study will assess reproducibility of the Pathria grading scale for FJ degeneration and of quantitative measurements such as FJ space width and FJ angulation.

Participants needed: 12
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Sklifosovsky Institute of Emergency CareUpdated: Jul 1, 2026Locations: 1
Eligibility criteria

availability of CT scans covering the T9-L3 vertebrae; [+1]

bone mineral density of the vertebrae of <100 HU; [+4]

Status: Recruiting

Dose Escalation Pilot Study to Evaluate the Safety of Alocyte for the Treatment of Facetogenic Back Pain

The purpose of this study is to see if the use of Alocyte (cord blood plasma plus mononucleic cells) will be safe, well tolerated, and whether it causes any side effects. The study will also examine if the use of the Investigational Product (IP) is able to reduce local inflammation or alleviate Facetogenic back pain

Participants needed: 15
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Alimorad FarshchianUpdated: Jan 13, 2026Locations: 1
Eligibility criteria

Subjects age > 18 years at the time of signing the Informed Consent Form. [+8]

Previous surgical intervention for back pain [+29]

Status: Recruiting

MRI-Guided Cryoablation to Alleviate Pain in Head, Neck and Spine

The objective of this study is to provide pain relief to patients with facet joint disease or head and neck pain related to compression of a nerve root. The goal is to provide palliative care with superior efficacy and longer relief compared to current methods.

Participants needed: 50
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Brigham and Women's HospitalUpdated: Aug 8, 2023Locations: 1
Eligibility criteria

Participants must be willing and able to sign a written informed consent documen... [+5]

Contraindications to MRI and Gadolinium- (i.e. estimated Glomerular Filtration R... [+1]