Health Trials

Familial Chylomicronemia Syndrome (FCS)

1

Review clinical trials related to Familial Chylomicronemia Syndrome (FCS). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

CS-121 APOC3 Base Editing in FCS

This is an open-label, single-arm, dose-escalation Phase I clinical trial to evaluate the safety, tolerability, pharmacodynamics (PD), and pharmacokinetics (PK) of CS-121, an in vivo base editing therapy delivered by lipid nanoparticles targeting APOC3, in adult participants (18-55 years) with familial chylomicronemia syndrome (FCS).

Participants needed: 15
Trial details
Phase: Early Phase 1Age: 18-55Biological sex: AllType: InterventionalSponsor: CorrectSequence Therapeutics Co., LtdUpdated: Feb 11, 2026Locations: 1
Eligibility criteria

Male or female aged 18 to 55 years (inclusive) at the time of signing informed c... [+4]

Currently participating in another interventional clinical study, or last use of... [+9]

Read more