First-line Treatment Failure Nasopharyngeal Carcinoma

1

Review clinical trials related to First-line Treatment Failure Nasopharyngeal Carcinoma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Iparomlimab and Tuvonralimab Combined With Nimotuzumab in Recurrent or Metastatic NPC After First-line Treatment Failure: A Single-arm Phase IIa Clinical Trial

This study aims to preliminarily explore the efficacy and safety of Iparomlimab and Tuvonralimab in combination with Nimotuzumab for the treatment of recurrent/metastatic nasopharyngeal carcinoma (NPC). It is expected to investigate a novel therapeutic regimen with improved efficacy and enhanced safety for recurrent/metastatic NPC, thereby providing robust evidence-based medical support for the application of dual-target immune checkpoint inhibitors in nasopharyngeal carcinoma therapy

Participants needed: 41
Trial details
Phase: Phase 2Age: 18-70Biological sex: AllType: InterventionalSponsor: Sun Yat-sen UniversityUpdated: Jan 23, 2026Locations: 1
Eligibility criteria

ECOG performance status score of 0-1; [+6]

History of other malignancies (except adequately treated non-melanoma skin cance... [+12]