Free Tissue Transfer

4

Review clinical trials related to Free Tissue Transfer. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Post-market, Real-world Experience: Expanding Access to Care by Incorporating the Symani® Surgical System and Enabling Surgeons

The objective of this study is to evaluate the Symani System's safety and effectiveness for microsurgical anastomosis during free tissue transfer surgery and lymphovenous anastomosis surgery. The primary endpoints are: * Effectiveness- Rate of intraoperative anastomosis patency at first attempt. * Safety- Freedom from device-related adverse events. Participants will receive treatment as standard of care and be asked to: * Allow the researchers to access and use their information. * If participants are undergoing a lymphedema procedure, they will be asked to undergo a questionnaire as part of the study. * Participants will be asked to comply with the follow-up visits and complete all study procedures/questionnaires as outlined in the protocol.

Participants needed: 455
Trial details
Age: 22+Biological sex: AllType: ObservationalSponsor: MMI (Medical Microinstruments, Inc.)Updated: Jul 13, 2026Locations: 6
Eligibility criteria

At least 22 years of age [+9]

Patients who are incapable and/or unwilling to provide informed consent [+25]

Status: Recruiting

CONNECT: A Multi-Cohort, Prospective Investigation of the Symani® Surgical System

The objective of this clinical study is to evaluate the Symani System's safety and effectiveness for microsurgical anastomosis during free tissue transfer surgery and lymphatic surgery. The primary endpoints are: Effectiveness: Clinical Success, defined as intraoperative anastomosis patency. Safety: Freedom from device-related serious adverse events prior to discharge from the index hospitalization, as adjudicated by a Clinical Events Committee. Participants will receive treatment as standard of care and be asked to: Allow the researchers to access and use their information. If participants are undergoing a therapeutic lymphatic procedure, they will be asked to complete a questionnaire and undergo lymphedema volume assessments as part of the study. If participants are undergoing a prophylactic lymphatic procedure, they will only be asked to undergo limb volume assessments. Participants will be asked to comply with the follow-up visits as outlined in the protocol.

Participants needed: 180
Trial details
Age: 18-100Biological sex: AllType: InterventionalSponsor: MMI (Medical Microinstruments, Inc.)Updated: Apr 2, 2026Locations: 1
Eligibility criteria

Adults, according to the local law [+11]

Patients who are not capable and/or unwilling to provide informed consent [+22]

Status: Recruiting

A Post-market, Real-world Experience: Expanding Access to Care by Incorporating the Symani® Surgical System and Enabling Surgeons

The objective of this study is to evaluate the Symani System's safety and effectiveness for microsurgical anastomosis during free tissue transfer surgery and lymphovenous anastomosis surgery. The primary endpoints are: * Effectiveness- Rate of intraoperative anastomosis patency at first attempt. * Safety- Freedom from device-related adverse events. Participants will receive treatment as standard of care and be asked to: * Allow the researchers to access and use their information. * If participants are undergoing a lymphedema procedure, they will be asked to undergo a questionnaire as part of the study. * Participants will be asked to comply with the follow-up visits and complete all study procedures/questionnaires as outlined in the protocol.

Participants needed: 455
Trial details
Age: 22+Biological sex: AllType: ObservationalSponsor: MMI (Medical Microinstruments, Inc.)Updated: Mar 5, 2026Locations: 4
Eligibility criteria

At least 22 years of age [+9]

Patients who are incapable and/or unwilling to provide informed consent [+25]

Status: Not yet recruiting

A Global, Prospective, Real-World, Investigation of the Symani® Surgical System for Microsurgical Anastomosis

The objective of this clinical study is to evaluate the Symani System's safety and effectiveness for microsurgical anastomosis during free tissue transfer surgery and lymphatic surgery. The primary endpoints are: * Effectiveness: Clinical Success, defined as intraoperative anastomosis patency. * Safety: Freedom from device-related serious adverse events prior to discharge from the index hospitalization, as adjudicated by a Clinical Events Committee. Participants will receive treatment as standard of care and be asked to: * Allow the researchers to access and use their information. * If participants are undergoing a therapeutic lymphatic procedure, they will be asked to complete a questionnaire and undergo lymphedema volume assessments as part of the study. If participants are undergoing a prophylactic lymphatic procedure, they will only be asked to undergo limb volume assessments. * Participants will be asked to comply with the follow-up visits as outlined in the protocol.

Participants needed: 1,000
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: MMI (Medical Microinstruments, Inc.)Updated: Dec 10, 2024
Eligibility criteria

Adults, according to the local law [+12]

Patients who are not capable and/or unwilling to provide informed consent [+23]