Health Trials

Fuchs

2

Review clinical trials related to Fuchs. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Descemet Endothelial Thickness Comparison Trial II

Descemet Endothelial Thickness Comparison Trial (DETECT) II is a multi-center, outcome assessor-masked, placebo-controlled clinical trial randomizing 60 patients with Fuchs endothelial dystrophy to DMEK versus Descemet Stripping Only (DSO) with adjunctive Ripasudil.

Participants needed: 60
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Stanford UniversityUpdated: May 8, 2026Locations: 8
Eligibility criteria

Dysfunctional endothelium from FECD with few guttata extending beyond 4.5 mm [+4]

Aphakia, anterior chamber IOL or scleral fixated IOL in study eye prior to or an... [+9]

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Status: Recruiting

DT-168 in Keratoplasty Patients With Fuchs Endothelial Corneal Dystrophy

The purpose of this study is to evaluate the pharmacodynamics, safety, and tolerability of DT-168 Ophthalmic Solution in pre-keratoplasty patients with Fuchs endothelial corneal dystrophy.

Participants needed: 28
Trial details
Phase: Phase 2Age: 30+Biological sex: AllType: InterventionalSponsor: Design Therapeutics, Inc.Updated: Dec 29, 2025Locations: 2
Eligibility criteria

Participant is scheduled to undergo a keratoplasty for management of FECD indepe... [+4]

Any ocular or medical condition in the study eligible eye which is clinically si... [+9]

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