Status: Recruiting
A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)
In this clinical trial, the safety, tolerability, and preliminary antitumor activity of ziftomenib in combination with imatinib will be evaluated in adults with gastrointestinal stromal tumors (GIST) who have been treated previously with imatinib.
Participants needed: 157
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Kura Oncology, Inc.Updated: Feb 5, 2026Locations: 32
Eligibility criteria
Documented diagnosis of advanced/metastatic KIT-mutant GIST. [+7]
Diagnosis of GIST without a KIT mutation or with a T670X KIT mutation. [+10]